Immune responses to pathogen groups Flashcards
(27 cards)
Innate cell needed for inflammation
Macrophage
Mediators needed for inflammation
Those that secrete inflammatory cytokines:
- TNF
- IL-1
- IL-6
Effector innate cell needed to remove virus
NK cell
Effector innate cell needed to remove IC bacteria
Macrophage
Effector innate cell needed to remove EC bacteria
Neutrophil
Th subtype needed to promote effector functions in infected tissue - virus
Th1
IL-2 helps CD8
Th subtype needed to promote effector functions in infected tissue - IC bacteria
Th1
need IFNgamma to form granuloma
Th subtype needed to promote effector fx in infected tisse - EC bacteria
Th17
Th1
Need inflam
Phagocytes recruited
Are CD8 needed for host defence against viruses?
Yes
Are CD8 needed for host defense against IC bacteria?
Not unless bacteria gets into cytosol
Are CD8 needed for host defense against EC bacteria?
No
Are Ab needed for host defense against viruses?
No, but important for vaccine defense
IgG
Are Ab needed for host defense against IC bacteria?
Not crucial
Are Ab needed for host defense against EC bacteria?
Yes
IgG
For which is complement needed against? (Only 1)
EC bacteria
Innate cell needed for inflammation against yeast
Macrophage
INnate cell needed for inflammation against helminths/allergies
Mast cell
Innate mediator needed for inflammation against yeast
TNF
IL-1
IL-6
Innate mediator needed for inflammation against helminths/allergies
HM
Effector innate cell needed to remove yeast
neutrophils
Effector innate cell needed to remove helminths/allergies
Eosinophil
mast cell
Th subtype needed to promote effector fxns in yeast infection
Th17
Need IL-17 to recruit neutrophils
Th subtype needed to promote effector fxn in helminth/allergies
Th2
Need IL-5 to recruit eosinophils
Are CD8 needed against yeast?
No (EC)
