Immune system Flashcards
(29 cards)
Main cells of the immune system:
- Monocytes
- Macrophages
- Lymphocytes
2 branches of the immune system:
Innate and adaptive
Primary lymphoid organs
- Thymus
- Bone marrow
Secondary lymphoid organs
- Lymph nodes
- Spleen
- Gut-associated lymphoid tissue (GALT)
Primary function of GALT
Help to protect the body from pathogens and foreign substances that are ingested through food and drink
What is an antigen?
Molecule or molecular structure that is recognized by the immune system as foreign or non-self
Where can antigens be found?
Surface of pathogens like bacteria, virus, fungi and parasites
What does antigens do?
They are capable of eliciting the production of antibodies or activating immune cells
What are some nonspecific cells in the innate immune response:
- Phagocytes
- Natural killer cells
Primary types of APC’s
- Dendritic cells
- Macrophages
- B cells
How are the leukocytes form?
Form by hematopoiesis in bone marrow
Example of myeloid cells:
- Neutrophils
- Basophils
- Monocytes
- Dendritic cells
- Macrophages
What do myeloid cells contribute:
Innate response
What do lymphoid cells contribute:
Adaptive response
Classification of immune cells:
- Phagocytes
- Granulocytes
- Antigen-presenting cells
Estudien la tabla:)
What happens in graves?
Increase hyperthyroidism
What happens in Hashimoto?
Decrease hypothyroidism
Type I in Coombs and Gell’s classification:
Allergy, acute hypersensitivity
Type II in Coombs and Gell’s classification:
Antibody -dependent cytotoxicity
Type III in Coombs and Gell’s classification:
Immune complex disease
Type IV in Coombs and Gell’s classification:
Delayed type of hypersensitivity/ cell-mediated immune memory response
Characteristics of the hyperacute rejection
- Minutes after transplant
- Initiated by humoral immunity
Characteristics of acute rejection
- Highest risk window one week to three months after transplant
- Mediated by cellular immunity
Characteristics of chronic rejection
- Months to years after transplantation
- Fibrosis of blood vessels