Quizzes Flashcards

(90 cards)

1
Q

C: What is the primary pathological process that leads to the development of coronary artery disease (CAD)?

A

Atherosclerosis

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2
Q

C: In a normal ECG waveform, what does P-wave represent?

A

Atrial depolarization

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3
Q

C: What role does vascular dysfunction play in the pathophysiology of essential hypertension, and how does it contribute to elevated blood pressure levels?

A

Vascular dysfunction causes a decrease in peripheral vascular resistance

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4
Q

C: Which physiological factors related to the kidneys are implicated in the development of essential hypertension?

A

Dysregulation of the renin-angiotensin-aldosterone system (RAAS)

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5
Q

C: What is the primary function of antigen-presenting cells (ACPs) in the immune system?

A

To present antigens to T cells

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6
Q

C: True or false. Bacteria and parasites are not antigens

A

False

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7
Q

C: What is the most common underlying cause of atherosclerosis, contributing to the development of coronary artery disease?

A

Low-density lipoprotein (LDL) cholesterol

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8
Q

C: During which phase of the cardiac does the ventricle contract, causing a rise in ventricular pressure and closure of the atrioventricular valves?

A

Ventricular systole

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9
Q

C: What is the role of the atrioventricular node in the cardiac conduction system?

A

Delaying the impulse transmission to the ventricles

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10
Q

C: Which component of the immune system provides rapid and specific protection upon re-exposure to a previously encountered pathogen?

A

Memory immunity

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11
Q

C: True or False. Antigens plays an important role in the production of antibodies

A

False

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12
Q

C: How does the narrowing of coronary arteries due to atherosclerosis affect myocardial oxygen supply and demand?

A

It decreases myocardial oxygen supply and increases demand

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13
Q

C: Which is the most frequent etiology of heart failure?

A

Hypertension

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14
Q

C: Which of the following is NOT a component in the pathophysiology of hypertension?

A

Vasodilation

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15
Q

C: If too little blood flows into the ventricles, you might think of:

A

Diastolic heart failure

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16
Q

C: Which immune rejection can be avoided in transplantation using an immunosuppressing treatment?

A

Acute

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17
Q

C: The first sound in the phonocardiogram in the cardiac cycle is associated with:

A

Mitral and Tricuspid valve closes

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18
Q

C: Which is an important chemical component in the local blood regulation of blood pressure?

A

NO

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19
Q

C: Where is released the hormone renin?

A

From the kidney

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20
Q

C: Choose the common preventable risk factor for cardiovascular disease?

A

Hypertension

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21
Q

R: What is the most common risk factors for the development of COPD?

A

Cigarette smoking

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22
Q

R: How is COPD diagnosed?

A

By measuring the FEV1/FVC ratio using spirometry

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23
Q

R: Which type of inflammation is most common in asthma?

A

T2-type inflammation

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24
Q

Which cells are predominantly found in the inflammatory infiltrate of asthma?

A

Eosinophils, mast cells, basophils, neutrophils, monocytes, and, macrophages

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25
What is the role of oxidative stress in COPD?
It contributes to lung injury and inflammation
26
Which of the following is NOT listed as a pathological feature of COPD?
Pulmonary arteriole dilation
27
Which of the following is NOT a feature of the chronic inflammation observed in COPD?
Decreased numbers of macrophages and neutrophils
28
How is the airflow limitation defined in the context of COPD?
FEV1/FVC ratio of 0.7
29
During a normal quiet breathing cycle, the process of expiration is mainly a result of which of the following?
Passive recoil of the lungs and chest wall
30
What role do environmental allergens play in asthma?
Triggering asthma exacerbations
31
Which factors contribute to the development of asthma?
Genetic and environmental factors
32
What is the effect of altitude on oxygen transport in the blood?
Decreased partial pressure of oxygen in arterial blood, leading to reduced hemoglobin saturation
33
Which of the following interventions is likely to improve FEV1 in a patient with reversible obstructive lung disease?
Administration of a short-acting beta-agonist inhaler
34
What is the role of oxidative stress in COPD?
It leads to reduced lung function
34
How does airway remodeling affect asthma?
Contributes to the chronicity and severity of asthma
35
What leads to the chronic inflammation observed in COPD?
Chronic inhalation of irritants like cigarette smoke and air pollutants
36
In the diagnosis of obstructive lungs diseases, such as asthma and COPD, an FEV1/FVC ratio less than 70% typically indicates:
Obstructive lung disease
37
What is the role of airway epithelial cells in asthma?
Initiating T2-type immune responses
38
What does FEV1 primarily measure in a pulmonary function test?
The volume of the air that can be forcibly exhaled in the first second of a breath
39
Which of the following does NOT contribute to the pathophysiology of COPD according to the document?
High levels of physical activity
40
Which cytokines are involved in the pathogenesis of asthma?
IL-25, IL-33 and TSLP
41
What is asthma characterized by?
chronic airway inflammation and variable remodeling
42
Which of the following best describes the primary function of surfactant in the lungs?
To decrease the surface tension within alveoli, making it easier for them to expand during inspiration
43
Which are the main pathological features of COPD?
Obstructive bronchiolitis, emphysema and mucus hyper secretion
44
What is the primary trigger for acute exacerbations in COPD?
Respiratory viral infections
45
Which cytokines are involved in epithelial damage and repair in asthma?
IL-4, IL-9 and IL-13
46
Which of the following changes in the blood would lead to an increase in respiratory rate?
Decreased partial pressure of arterial oxygen (PaO2)
47
True or False. Kidneys regulate calcium metabolism
True
48
True or false. Infections of kidneys can produce an intrarenal kidney failure
True
49
True or false. A glomerular filtration rate of 120 is normal
False
50
True or false. Kidneys get less than 5% of the cardiac output
False
51
True or false. Cardiac failure could be a cause of pre renal failure
True
52
Which is the functional unit of the kidney?
Nephron
53
True or false. If the blood flow in the glomerulus decreases then the glomerular filtration rate increases
False
54
True or false. Autonomous nervous system is a regulating mechanism of glomerular filtration rate
True
55
Which is NOT a main function of the nephron?
Erythropoyetin synthesis
56
True or false. Systemic blood pressure has a minimal effect in the glomerular filtration rate
False
57
True or false. Kidneys regulate pH in blood
True
58
True or false. The main function of tubular system is filtration of blood
False
59
True or false. Kidneys have the capability of electrolyte balance
True
60
True or false. Renal failure can be measured by Glomerular Filtration Rate
True
61
True or false. Vasoconstriction of the afferent artery will decrease the pressure in the glomerulus
True
62
True or false. The urine formation begin in the bladder
False
63
True or false. Creatinine is NOT an indicator of Glomerular filtration rate
False
64
True or false. Prostate cancer could be an intrarenal cause of kidney failure
False
65
True or false. A healthy person filtrates proteins in the glomerulus
False
66
True or false. Accumulation of urea in blood is a key sign of kidney failure
True
67
True or false. The urinary excretion depends on the filtration rate of the glomerulus
True
68
True or false. Glucose is easily filtered in the kidneys
True
69
Main function of platelets?
Blood coagulation
70
Sickle cell anemia is characterized by:
Erythrocytes in the shape of a sickle due to a mutation in hemoglobin
71
What primarily regulates erythropoiesis in response to hypoxia?
The kidney releases erythropoietin
72
Main function of leukocytes?
Defense against infectious agents
73
Which leukocytes is most effective in fighting viral infections?
Lymphocytes
74
Which cell plays a crucial role in primary hemostasis?
Platelets
75
Monocytes are leukocytes that:
Phagocytize pathogens
76
Which of the following leukocytes is primarily responsible for the humoral immune response?
B lymphocytes
76
Hemophilia is a genetic disorder that primarily affects:
Coagulation factor activity
77
What is the approximate lifespan or erythrocytes in human circulation?
120 days
78
Which laboratory finding is most indicative or iron-deficiency anemia?
Low serum ferritin
79
Which statement about hemoglobin is correct?
It enables the transport of oxygen and carbon dioxide
80
What is the primary function of erythrocytes?
Transport of oxygen and carbon dioxide
81
What factor primarily stimulates the production of erythrocytes?
Erythropoietin
82
Leukemia is characterized by:
Uncontrolled and abnormal production of leukocytes
83
The presence of which antigen determines if a person has type A blood?
Antigen A
84
Thrombocytopenia is characterized by:
Decrease in the number of platelets
85
Which of the following is a primary cause of polycythemia vera?
A mutation leading to increased sensitivity of erythroid precursors to growth factors
86
Which type of anemia results from the autoimmune destruction of gastric parietal cells?
Iron-deficiency anemia
87
In the ABO blood group system, which type of blood is considered the universal donor?
Type O
88