Immunity Flashcards
(31 cards)
3 types of immunity
Natural
Artificial
Passive
Disease causing organisms are called
Pathogen
Substance capable of generating an immune response
Antigen
Organism that harbors a virus, bacteria, or parasite
Host
Antibody-protein produced by B cells of the host to bind…
antigen
Cells of the immune system are called
WBCs or Leukocytes
Phagocytes types (3)
macrophages
neutrophils
dendric cells
Innate immune system cells
phagocytes, mast cells, eosinophils, basophils, natural killer cells
Adaptive Immune System cells
lymphocytes and dendritic cells
Lymphocytes are
T & B cells
Mechanical Barriers (6)
Epidermis Intrinsic epithelial Saliva Coughing/sneezing Urine (flushing) Cilia
Chemical barriers (4)
Sebum
Skin acidity
beta-defensins
gastric juice
Commensal microflora as barrier
urinary and gastrointestinal tracts and skin - biological barriers compete with pathogenic bacteria for food and space
1st line of defense
Innate immune system
How is the innate immune system developed?
Present at birth
Specificity?
None
Enhanced by second exposure?
No
Memory?
None
Uses…
cellular and humoral components
Activates…
Adaptive immune responses
PAMP
Pathogen Associated Molecular Patterns - structural elements common to broad classes of microbes and are very hard to change
Innate immune system slows…
growth of infectious agents until adaptive immune response kicks in
PAMPs bind to
pattern recognition receptors (PRRs)
PRRs are on
immune cells of innate immune system - phagocytes