immunity and disease Flashcards

1
Q

describe innate immunity

A

non specific, mechanisms are present before infection

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2
Q

function of skin for innate immunity?

A

outer layer of keratin forms a mechanical barrier, dead skin cells are sloughed off, sweat and oils contain anti-microbial chemicals

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3
Q

functions of mucous membranes for innate immunity?

A

normal flow of mucus washes bacteria and virus off mucous membranes, cilia protect the respiratory tract, acid in the stomach and vagina

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4
Q

chemical barriers within innate immunity?

A

proteins and interferons

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5
Q

cellular defences of innate immunity?

A

phagocytosis

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6
Q

examples of granulocytes?

A

neutrophils, eosinophils, basophils

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7
Q

function of granulocytes?

A

remove dead cells and micro-organisms

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8
Q

examples of monocytes?

A

macrophages

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9
Q

function of monocytes?

A

serve as filters for trapping microbes

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10
Q

what is adaptive immune response?

A

specific, cell-mediated and humoral immunity

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11
Q

where are lymphocytes produced?`

A

bone marrow.

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12
Q

where do B cells and T cells mature?

A

B cells - mature in bone marrow, then concentrate in lymph nodes and spleen. T cells - mature in thymus

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13
Q

function of B cells

A

secrete and produce antibodies, involved in humoral immunity and recognise pathogens outside of cells. they become memory cells

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14
Q

function of T cells

A

directly attack invaders - some can recognise and destroy cancer cells

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15
Q

how do vaccinations work?

A

stimulates own immune system to elicit an adaptive immune response to prevent further infection

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