Immunity & Cellular Regulation

Question 1

To what receptors does Epinephrine attach to ?

Answer 1

• Alpha 1
• Beta 1 & 2

Question 2

What does the Alpha 1 receptor control ?

Answer 2

vasoconstriction

Question 3

What does the Alpha 2 receptor control ?

Answer 3

vasodilation

Question 4

What does the Beta 1 receptor control ?

Answer 4

increased HR (how fast) & contractility (how strong)

Question 5

What does the Beta 2 receptor control ?

Answer 5

bronchodilation

Question 6

What are some sign/symptoms of Anaphylaxis ?

Answer 6

• angioedema (swelling of mouth, and tongue)
• feeling of impending door caused by constriction of airway, dizziness, wheezing, stridor, tachypnea, coughing, bronchoconstriction, stop breathing
• increased HR, cardiac arrest, dysrhythmias
• decreased BP
• systematic (all over the body)

Question 7

What are the therapeutic uses of Epinephrine ?

Answer 7

• treat symptoms of anaphylaxis
• asthma
• shock
• CPR

Question 8

What are the therapeutic uses of Oseltamivir ?

Answer 8

• treats symptoms of the Flu
• treats uncomplicated acute illness cause by the flu in adults

Question 9

What are the therapeutic uses of Acyclovir ?

Answer 9

• lessens effects of shingles
• antiherpes virus (only limits time it occurs)

Question 10

What is the therapeutic use of Interferon alfa-2a ?

Answer 10

• treat chronic hepatitis C

Question 11

What is the therapeutic use of HAART therapy ?

Answer 11

disrupts HIV virus replication
- can keep pt undetectable and untransmissible

Question 12

What are the therapeutic uses of Doxorubicin ?

Answer 12

• tumors and hematologic cancers

Question 13

What are the therapeutic uses of Cyclophosphamide ?

Answer 13

• cancer
• RA and lupus

Question 14

What are the therapeutic uses of Vincristine ?

Answer 14

• acute leukemias
• breast, lung cancer
• testicular, and ovarian cancer
• Kaposi’s sarcoma

Question 15

What is the therapeutic use of Tamoxifen ?

Answer 15

treats estrogen-receptor metastatic breast cancer

Question 16

What is the therapeutic use of Trastuzumab ?

Answer 16

treat metastatic breast cancer

Question 17

In a HIV + pt how does their viral load and CD4 look like ?

Answer 17

high viral load and low CD4 count

Question 18

What is Cell Cycle Nonspecific (CCNS) treatment ?

Answer 18

not specific to mitosis and will kill cells in any phase
-Ex.) doxorubicin, cyclophosphamide

Question 19

What is Cell Cycle Specific (CCS) treatment ?

Answer 19

kills cells in a specific stage in mitosis
- Ex.) vincristine

Question 20

What is stomatitis ?

Answer 20

sores in mouth that are painful and pt may not want to eat
- happens in chemo pt’s

Question 21

What is Thrombocytopenia ?

Answer 21

decreased platelet count
- watch for bruising and bleeding

Question 22

What is Neutropenia ?

Answer 22

low WBC count

Question 23

With anaphylaxis where do you administer the Epinephrine ?

Answer 23

IM

Question 24

What is Racemic Epinephrine ?

Answer 24

inhaled Epi
- good for pt’s with stridor (works on all sites)

Question 25

What is cell cycle nonspecific (CCNS) ?

Answer 25

kills cells in any phase
- not specific to mitosis

Question 26

What is primary immunodeficiency ?

Answer 26

born with this and a genetic mutation is causing a depletion

Question 27

What is secondary immunodeficiency ?

Answer 27

intentional or from adverse effect of tx