Immunity to Microorganisms Flashcards Preview

Unit 3 Micro and Immunology > Immunity to Microorganisms > Flashcards

Flashcards in Immunity to Microorganisms Deck (22)
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1
Q

What makes an organism a pathogen?

A

Its ability to successfully evade the immune system

2
Q

In most cases what kills microorganisms within the body?

A

Phagocytic cells

3
Q

What do Cytotoxic T cells kill?

A

Infected host cells

4
Q

What is the function of specific immunity?

A

To enhance the uptake of microorgaisms by phagocytic cells or to enhance the activity of phagocytic cells

5
Q

What are the barriers that comprise the innate immune system?

A
1- Skin
2- pH barriers
3- Flushing
4- Lysozyme
5- Phagocytes
6- Compliment
6
Q

What does lysozyme destroy?

A

the cross links in bacterial cell walls

7
Q

What are virulence factors?

A

mechanisms that bacteria have that give them the ability to evade host defenses

8
Q

What is the primary adaptive immune response of the body?

A

antibody

9
Q

What is the role of antibody?

A
1- prevent the attachment to epithelium
2- trigger compliment
3- bind to antiphagocytic M proteins or capsules
4- Neutralize toxins
5- neutralizing spreading factors
6- opsonize bacteria
10
Q

What is a characteristic of facultative intracellular parasites?

A

ability to survive within a phagosome (with help of T3SS)

11
Q

What kills bacteria that can survive in normal macrophages?

A

activated macrophages

12
Q

What is the function of activated macrophages?

A

non-specific kil;ing

13
Q

Is there long term immunity from activated macrophages?

A

no there is no because it is not T cell mediates so no memory cells can be made

14
Q

Where does immunological memory exist, cells or serum?

A

Cells

15
Q

Which cells in specific transfer specific immunity?

A

CD4+

16
Q

What mediates specific kiiling? What mediates non-specific killing?

A

specific killing= T cells

non-specific killing= activated macrophages

17
Q

The mechanism of antigen presentation is important for what?

A

the type of immune response that develops

18
Q

What cells are important for immunity to parasites?

A

CD8+

19
Q

Which cytokines does Tubercoid leprosy favor?

A

Th1

20
Q

Which cytokines does Leprosy leprosy favor?

A

Th2

21
Q

What does Th1 stimulate?

A

cell mediated immunity

22
Q

What does Th2 stimulate?

A

antibody immunity