Immuno Flashcards

(11 cards)

1
Q

targets materials labeled with compliment, IgG or collectins

A

Neutrophils

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2
Q

binds to IgG to enhance phagocytosis

A

Neutrophils

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3
Q

how does rolling occur

A

sialyl lewis X binds to selectins on endothelial surface

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4
Q

how does crawling occur

A

integrins bind to ICAM on the endothelial surface

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5
Q

how does transmigration occur

A

neutrophils bind to PECAM-1

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6
Q

what color are neutrophilic cytoplasmic granules

A

pink

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7
Q

how long do monocytes macrophages stay in circulation

A

about 3 days

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8
Q

what cytokines can macrophages secrete

A

IL-1
IL-6
IL-8
TNF-alpha

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9
Q

where do dendritic cells reside

A

epithelial and lymphoid tissue

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10
Q

explain the activation of dendritic cells

A

PAMP exposure stimulates maturation, causing the release of IL-2 and increases expression of B7 and C5a receptors

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11
Q

what cytokines stimulate natural killer cells

A

IFN- alpha and beta

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