Immuno Flashcards
(11 cards)
targets materials labeled with compliment, IgG or collectins
Neutrophils
binds to IgG to enhance phagocytosis
Neutrophils
how does rolling occur
sialyl lewis X binds to selectins on endothelial surface
how does crawling occur
integrins bind to ICAM on the endothelial surface
how does transmigration occur
neutrophils bind to PECAM-1
what color are neutrophilic cytoplasmic granules
pink
how long do monocytes macrophages stay in circulation
about 3 days
what cytokines can macrophages secrete
IL-1
IL-6
IL-8
TNF-alpha
where do dendritic cells reside
epithelial and lymphoid tissue
explain the activation of dendritic cells
PAMP exposure stimulates maturation, causing the release of IL-2 and increases expression of B7 and C5a receptors
what cytokines stimulate natural killer cells
IFN- alpha and beta