Immuno Deficiency And Drugs Flashcards
(13 cards)
1 yo boy came with repeated staphylococcus and enteovirus inf
PBS no b cells and dec level all ig
No lymph node
and follicles and germinal,centres missing
Ans: X linked agammaglobulinemia
Don’t give live vaccines
Repeated giardia infection
Airway infections
Gave false positive pregnancy test
False negative celiac
IgA deficiency
No cxray thymus
Tetany
digeorge- thymic cardiac and parathyroid defects
Mycobacteria’s infection and reduced IFN GAMMA
IL12 R DEF(dec Th1 response)
MSMD
AR
Eczema
Cold abscess due to staph a or candida
Which antibody is raised?
Job syndrome or hyper IgE
AD
Inc IgE and Eosinopils
Inc risk of all infections
Cant thrive
No germinal centres
No thymus and T cells
SCID
ADA def (AR)
DEF IL-2R(XR)
Ataxia
Spider aNGIOMAS
Inc AFP
Mucosal infections
Ataxia telengiectasia
Dec IgA G and E
ATM gene mut can’t detect DNA damage
Inc risk of lymphoma leukemia
Bacterial and pneumocystis inf
No germinal centres
Baby boy
CD40L defective
No class switching
Hyper IgM syndrome
XR so boys
Thrombocytopenia eczema rec bact inf
Deformed platelets
Dec ig G and M
Inc IgE and A
Defective AP
Wiskott Aldrich
Water mnemonic
Late sep of cord after 30 days
Absent pus
Dysf neutrophils(inc in blood)
Impaired wound healing
Leukocyte adhesion deficiency type 1
AR
Def of integrin (CD18) on phagocytes
Impaired migration and chemotaxis
Granules in granule tree and platelets
Pancytopenia
Inc lymphocyte and macrophages
Progressive neurodeg
Lymphohidtocytosis
Albinism
Rec pyo Infection
periph neuropathy
PLAIN
Chediak higashi syndrome
Staphylococcus and aspergillus infection
Neutrophils containing intact bacteria
Nadph oxides defect
Chronic granulomatous disease
Transplant rejection
Thrombosis
Vasculitis and lymphocyte infiltration
Arteriosclerosis and organ damage fibrosis
Type 4 hypersensitivity in bm or liver esp
Hyper acute
Acute
Chronic
Graft vs host
