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HEME Micro & Immuno > Immunocompromised HPR > Flashcards

Immunocompromised HPR Flashcards

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1
Q

cough in M. tuberculosis vs. Pneumocystis jiroveci

A

Tub–> PRODUCTIVE cough;

P. jiroveci–> non-productive

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2
Q

Clinical signs of pneumonia are usually absent despite infiltrates on x-ray

A

Pneumocystis jiroveci

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3
Q

septate hyphae and conidia on the conidiophore

A

aspergillus fumigatus

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4
Q

pts with asthma and allergies–>

A

aspergillus fumigatus

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5
Q

Eosinophila and allergic aspergillosis (pulmonary infiltrates)

A

aspergillus fumigatus

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6
Q

fungus ball seen on xray–>mycelial masses

A

aspergillus fumigatus

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7
Q

hemoptysis due to FISTULAS

A

aspergillus fumigatus

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8
Q

Filamentous fungus; Normal flora of rice, bean

A

Fusarium solani

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9
Q

Medication-related Immunodeficiency

Corticosteroids–> bacteria

A

All bacteria, particularly M. tuberculosis

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10
Q

Medication-related Immunodeficiency

Corticosteroids–>Fungi

A

Pneumocystis jiroveci, Aspergillus f, Fusarium solani

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11
Q

Medication-related Immunodeficiency

Corticosteroids–> parasite

A

Strongyloides stercoralis

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12
Q

Medication-related Immunodeficiency:

TNF-α inhibitors

A

Listeria monocytogenes

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13
Q

Medication-related Immunodeficiency:

Rituximab (mAb to CD20)

A

Babesia microti

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14
Q

pulmonary and peripheral eosinophilia

A

Strongyloides stercoralis

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15
Q

transient, raised, red, serpiginous lesions over buttocks and lower back

A

Strongyloides stercoralis

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16
Q

HBV reactivation

A

Rituximab

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17
Q

TB reactivation

A

TNF-α inhibitors

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18
Q

pate, contaminated milk, soft cheeses, coleslaw

A

Listeria monocytogenes

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19
Q
  • Internalin
  • Listerolysin O (LLO)
  • Propels through cytosol via actin polymerization
A

Listeria monocytogenes

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20
Q

Clay-colored bowel movements;

Dark urine

A

Hepatitis B Virus

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21
Q

Asplenic patients

A

Encapsulated (S. pneumo; H. influ; N. menin)
Babesia!!
Capnocytophaga canimorsus

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22
Q

Streptococcus pneumoniae

Haemophilus influenzae

Neisseria meningitidis

A

Encapsulated;
Asplenic Patient;
Humoral Immunodeficiency

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23
Q

Capnocytophaga canimorsus found in what patient pop?

A

asplenic

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24
Q

alpha-hemolysis (green zone around colonies)

Study These Flashcards
A

Streptococcus pneumoniae

Viridans Streptococci

25
Capsule is anti-phagocytic | • IgA protease
Streptococcus pneumoniae
26
Meningitis in very young (
Streptococcus pneumoniae
27
causes MOPS: Meningitis, otitis media,pneumonia and sinusitis
Haemphilus influenzae
28
hocolate agar containing hematin (factor X) and NAD (factor V)
Haemphilus influenzae
29
Gun metal gray, hemorrhagic, necrotic patches
Neisseria meningitidis
30
Erythematous macules initially | Petechiae and purpura
Neisseria meningitidis
31
Culture on Thayer-Martin or chocolate agar
Neisseria meningitidis
32
Digital necrosis
Capnocytophaga canimorsus
33
Gram-negative of oropharynx of canines
Capnocytophaga canimorsus
34
Early post-transplant period (2 and 6 months): | Opportunistic pathogens:
Pneumocystis jiroveci, Aspergillus fumigatus Cryptococcus neoformans
35
Early post-transplant period (2 and 6 months): | Reactivation of latent pathogens:
CMV; Varicella zoster virus; BK virus; Toxoplasma gondii
36
>6 months post-transplant:
encapsulated bacteria.
37
Encapsulated yeast-like fungus
Cryptococcus neoformans
38
Meningitis in immunocompromised patients (e.g. early post transplant)
Cryptococcus neoformans
39
Bone marrow transplants = interstitial pneumonia leading cause of death
Cytomegalovirus
40
low birth weight, microcephaly, chorioretinitis | • Fetal damage most likely in 1st trimester
Cytomegalovirus
41
Hemorrhagic cystitis in bone marrow transplants
BK Virus
42
Polyomavirus family | • Small double-stranded DNA virus with icosahedral capsid
BK Virus
43
Virus to kidneys and UT - persists for the life
BK Virus
44
Consuming raw or undercooked, contaminated meat
Toxoplasma gondii
45
Ingesting water, soil, vegetables, or anything contaminated with feces of an infected animal (particularly cats)
Toxoplasma gondii
46
Pseudomonas aeruginosa desc.
* Aerobic, Gram-negative bacillus | * Polar flagella for motility
47
Widespread in moist environments
Pseudomonas aeruginosa
48
Grows as golden, β-hemolytic colonies on blood agar
Staphylococcus aureus
49
Coagulase-negative gram-positive cocci that Forms biofilms on catheters and indwelling devices
Staphylococcus epidermidis
50
White piedra – soft, pale | nodules on hairs of scalp and body
Trichosporon asahii
51
Subcutaneous lesions from injury following "traumatic implantation" by contaminated splinters or plant thorns
Scedosporium prolificans
52
Thin, pleomorphic, Gram-negative bacillus
Legionella pneumophila
53
WATER SOURCES such lakes, riverbanks
Legionella pneumophila
54
Herpesviridae, dsDNA | Varicella & shingles
VZV
55
a-hemolytic gram + cocci in chains Dental carries Subacute endocarditis
Viridans Streptococci
56
Anamorphic yeast White piedra Invasive infection (lung, kidneys, spleen)
Trichosporon Asahii
57
Filamentous fungus | SubQ lesions after implantations – thorns/splinters
Scedosproium prolificans
58
Dimorphic fungus, no yeast phase-barrel hyphae Harsh environments Chronic pulmonary form – cavity + relapse
Coccidioides Immitus
59
Progressive pulmonary disease similar to that of pulmonary TB  starts off w/ dyspnea and non-productive cough, eventually moving to productive cough
Histoplasma Capsulatum

HEME Micro & Immuno (11 decks)

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