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NURS 347 EXAM 5 UROLOGY > Immunologic Disorders Of Kidney > Flashcards

Immunologic Disorders Of Kidney Flashcards

1
Q

What are the 5 immunologic disorders of kidney?

A

Glomerulonephrtisis
Acute poststreoptococcal Glomerulonephrtisis
Chronic glomerulonephritis
Good pasture syndrome
Rapid progressive glomerulonephritis ( RPGN )

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2
Q

What is glomerulonephritis and it effects?

A

Inflammation of Glomeruli
Both kidneys equally

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3
Q

Although glomerulonephritis mainly inflames the glomeruli, it can also effect?

A

Tubular and interstitial change
With Vascular scarring
And hardening ( glomerulosclerosis ) of the kidneys

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4
Q

Glomerulonephritis is the what 3rd leading cause of what in the United States?

A

ESRD

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5
Q

What are associated conditions that can cause glomerulonephritis? (4)

A

Kidney infections
Nephrotix drugs
Immune disorders
Systematic diseases

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6
Q

There are two types of Glomerulonephrtisis what are they and examples? (2)
(2,3)

A

Acute
- sudden symptoms & revisibke

Chronic
- slow
- progressive
- irreversible renal failure

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7
Q

Acute poststreoptococcal Glomerulonephrtisis is most common in who? (3)

A

Children (5-7)
Young adults
Older adults (60)

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8
Q

What does acute psotstreptococcal Glomerulonephrtisis develop?

A

1-6 weeks after an infection of tonsils, pharynx, skin by nephrotoxic strains of group A B hemolytic streptoccoci
( from antibodies to strep antigen )

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9
Q

So since it’s infections of tonsils pharynx or skin, it’s important to ask the patient of past history of?

A

Sore throat or fever

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10
Q

Although the exact mechanism is unknown for APSGN, how does it effect the glomeuri? (3)

A

Tissue injury occurs as the antigen antibody complexes
And goes into the glomeruli
Causing inflammation

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11
Q

What are clinical manifestations of APSGN (9)
S as SMOKE!!!
E AS IN EDD

A

Edema
Hypertension
Oliguria ( small amount of urine )
Hematuria ( bleeding urine )
Proteinuria ( protein in urine )
Fluid retention
Abdominal or flank pain
Asymptotic
Smoky urine

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12
Q

Anagram to help me remember clinical manifestations for APSGN (9)

A

Edds
Hyper
Orgy
Head
Provides
Fluid
Flanky
Ass
Smoke

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13
Q

At first Edema will a show up where ___ then moves towards total body including ____(2)

A

Periorbital ( eyes )
Ascites & peripheral

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14
Q

Why does smoky urine occur in clinical manifestations for ASPGN?

A

Bleeding in upper urinary tract

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15
Q

Why does hypertension occur in ASPGN?

A

Because of the increase EFV ( cashing that edema )

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16
Q

How do you diagnosis ASPGN? (7)
Example or explain each
Second one example is most important!!

A

History & physical assessment
Streptozyme test
(Antistreptolysin-O ( ASO) tigers)!!
Renal biopsy - confirms
Dipstick urinalysis
Urine sediment microscopy
( erythrocytes & protein )
BUN& CREATINE test
- renal impariment

17
Q

Nursing Interprofessional & management of ASPGN
over how many people recover completely with conservative treatment?

A

95%

18
Q

Management of ASPGN is? (4)
Examples or explain each

A

Rest
- decreased inflammation & HTN

Restrict Sodium & fluids ( administer diuretics )
- describe edema

Restric protein
- decreased BUN

Antibiotics
Streptococcal infection present

19
Q

Prevention of ASPGN?

A

Early diagnosis & treatment of sore throats & skin lesions

20
Q

If the patient is positive with streptoccoci culture what do we want to give and teach patient?

As well what to do with skin infections?
Patient should do?

A

Antibiotics & take entire prescription
Personal hygiene
( stop spread )

21
Q

What is chronic Glomerulonephritis?

A

Syndrome of permanent and progressive renal fibrosis
Which can lead to ESRD

22
Q

Some people who develop chronic glomerulonephritis will never or either have what? (2)
( think of syndrome )

A

Never had history of kidney disease
Inheredied ( alport syndrome )

23
Q

Symptoms occur what for chronic glomerulonephritis?

A

Slowly and unware

24
Q

Chronic glomerukobephritis
Clinical manifestations are? (5)

A

Hematuria
Proteinuria
Urinary execration of formed elements ( RBCS, WBCS, CASTS)
Increase BUN
Increase Creatinine

25
Q

What’s the diagnosis of Chronic Glomerulonephritis? (7)
Think of the CENTs scan of C in Chronic
This is the NSAIDS ONE!!

A

History and physical exam
Exposure to drugs (NSAIDS)
Microbial infections
Viral infections
Evaluate for immune disorders
Ultrasound & cents scan
Renal biopsy

26
Q

What is the treatment of chronic glomerulonephritis?

A

Depends on the cause of it

27
Q

What is rapid progressive glomerulonephritis ( RPGN )?
It’s very ___ and you can loss renal function within ___

A

Glomerular crescent formations
Fast
Days or months

28
Q

How does Rapid Progressive Glomerulonephritis occur? (4)

A

Complications of inflammatory
Infectious disease
Systemic disease
Idiopathic

29
Q

What are clinical manifestations for RPGN? (5)

A

Hypertension
Edema
Proteinuria
Hematuria
RBC casts

30
Q

What are treatments of RPGN? (4)
Examples of each
Correcting what

A

Correct
fluid overload ( diuretics )
Hypertension ( anti HTN )
Uremia
( corticosteroids ( inflammation from bleeding )
Injury to kidney ( dialysis & transplant )

31
Q

Goals for RPGN? (2)

A

Cure or Control primary disease
Relieve symptoms

32
Q

What is good pasture syndrome

A

Autoimmune disease
Antibodies attack glomerular and basement membranes

33
Q

How does the antibodies attack glomerular in goodpasture syndrome?

A

Kidney and lung damage from antibody binding causes inflammatory reaction and complement activation

34
Q

Goodpasture syndrome is a what?
Happens at what age?

A

Rare disease
30-60

35
Q

What are clinical manifestations of good pasture syndrome? (3)

A

Flu like and pulmonary symptoms
Renal involmenr

36
Q

What are mangement of good pasture syndrome (6)

A

Corticosteroid
Immunosuppressive drugs
Plasmapheresis
Rituximab
Dialysis
Renal transplant

37
Q

What are the nursing prevention for Goodpasture syndrome? (2)

A

Smoking cessirstion
Respiratory distress

38
Q

Good pasture syndrome can be fetal from ? (2)

A

Hemorrhage & respiratory failure

NURS 347 EXAM 5 UROLOGY (16 decks)

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