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Flashcards in Immunology Deck (13):
1

Draw and name lymph node regions

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2

Diagram of Spleen lymph region

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3

Diagram Peyer's Patch

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4

High Endothelial Venules

Specialized blood vessels as point of enterance for lymphocytes to squeeze through into the lymph node

5

Follicle

B-cell area

Outer cortex of lymph node

6

Paracortical area

T cells diffusely distributed

adjacent to medullary cords (lower) and follicles (upper)

Flow in to center, DC and Macs, T-cell, B-cell

7

Germinal Center

Activated B-cells undergoing intense poliferation and differentiation into plasma cells

8

PALS

(spleen) Periarteriolar lymphoid sheath

Mainly T-cells

Surround primary arteriol like serpant

9

Marginal zone

(spleen) Surrrounds follical at intervals around PALS

Few T-cells, rich in macrophages, special resident noncirculating populatio of B-cells

Marginal Zone B Cells

10

MALT

GALT

Mucosal immune system

Gut-associated lymphoid tissue (includes tonsils, adenoids, appendix & Peyer's patches)

11

Payer's Patch

Antigen collected from lumin of GI (GALT), Upper resp. (NALT), Lower Airway (BALT) by M Cells (microfold)

Large centeral Follicle

 

12

Neutralization

Opsonization

Compliment Activation

Coating antigen(s) to destroy function

Coating of microbes targeting for phagocytosis/distruction

Coating - Fc region platform for complement binding

13

Th1

Th2

Th17

T(FH)

Induce Macrophages to increase killing power to distroy engulfed pathogens resistant to normal lysis conditions

Increases responses at mucosal surfaces (and parasitic infections) increase mucus, recrute eosinophils, IgE production

Promote responses with neutrophils (extracellular bacteria and fungal infections)

Resides in follicles, provide much of the help to B-cell activation to plasma cells