Immunology Flashcards

(46 cards)

1
Q

What is immunuology

A

The study of an organisms defense system in health and disease

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2
Q

Which three things is the immune system composed of

A

Organs (eg spleen)
Cells (t cells)
Molecules (eg antibodies)

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3
Q

What is the immune system

A

An organized system of organs cells and molecules that interact together to defend the body against disease

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4
Q

What are the 4 microbes

A

Viruses, bacteria, fungi, protozoa

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5
Q

What are disease causing microbes called

A

Pathogens

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6
Q

What is a primary lymphoid organ

A

Produces white blood cells

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7
Q

What is a secondary lymphoid system

A

Sites where the immune responses are initiated

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8
Q

What is the bone marrow purpose in the lymphoid system and is it primary or secondary

A

Produces stem cells which develop into the innate and adaptive cells, primary

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9
Q

What is the thymus purpose in the lymphoid system and is it primary or secondary

A

It is the school for white blood cells called t cells.
It is a primary lymphoid organ
The cells learn not to react to own body
Not many ‘pass’
Those that dont pass die

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10
Q

What is the spleen purpose in the lymphoid system and is it primary or secondary

A

Site of initiation for immune responses against blood borne pathogens
Secondary

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11
Q

What is the lymph nodes purpose in the lymphoid system and is it primary or secondary

A

Loxated along the lymphatic vesselsWhere lymph fluid from blood and tissue is filtered. Site of initiation of immune responses
Secondary

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12
Q

What are the three layers of the immune system

A

Chemical and physical barriers
Innate arm
Adaptive arm

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13
Q

What is the epidermis (outer) layer if the skin made up of

A

Dead cells, keratin, phagocytic immune cells

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14
Q

What is the dendritic cell (middle layer) of the skin made up of

A

Dendritic cells

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15
Q

What is the dermis layer (innermost) made up of

A

Connective tissue, collagen, and blood vessels and phagocytic immune cells

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16
Q

What does phagocyte mean

A

A cell that’s a big eater - this means that if there’s a cell that should not be there it will eat it and hopefully destroy it

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17
Q

What does lysozyme on the skin do

A

Breaks down bacterial walls

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18
Q

What does sebum do

A

It has a low ph meaning its acidic so will destroy cells

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19
Q

What does salt on th skin do

A

Will dry out the pathogens

20
Q

What is the outer layer of the mucous membrane called

21
Q

What is the middle layer of the mucous membrane called

22
Q

What is the inner layer of the mucous membrane called

A

Fibrous connective tissue

23
Q

What are the chemical defenses if the skin

A

Antimicrobial peptides, lysozyme, sebum, salt

24
Q

What does the epithelium layer of the mucous membrane do

A

The tightly packed live cells are physical barriers, they get constantly renewed, and have mucous producing goblet cells

25
Where are mucosal membranes
They line the parts of the body that lead to the outside and are exposed to air
26
How does the mucociliary elevator work
Cilia move mucous up thr the pharynx (image cilia like villi)
27
What are the 6 chemical defences of the mucosal surfaces
``` Stomach has low ph Call bladder, bile microbes cant grow Intestine digestive enzymes that brake down any pathogens that we might eat Mucus traps particles Defensins Lysozyme, tears and urine ```
28
What are the two arms of the immune system
Innate and adaptive defences
29
What are the two parts to the inate defense system
Surface barrier eg skin and mucous membranes | Internal defences eg phagocytes, natural killer cells, inflammation, antimicrobial proteins, fever
30
What are the two sections of the adaptive defense system
Humural immunity, Bcells | Cellular immunity, t cells
31
Is inate immunity fast or slow
Fast
32
Is adaptive immunity fast or slow
Slow
33
Is innate immunity specific and shows it have memory
No and no
34
Is adaptive immunity specific and does it have memory
Yes and yes
35
What is blood composed of
Plasma and cells
36
What 3 rhings is plasma made up of
Proteins, water and other solutes
37
What are the 3 types of formed elements in the blood
Platelets, white blood cells, red blood cells
38
Where di blood cells get made
Bone marrow
39
What are bone marrow stem cells known as
Hematopoiesis
40
Are erythroid cells red blood cells or white blood cells
Red blood cells
41
What are the two types of white blood cells
Myeloid and lymphoid
42
What are myeloid cells made up of
Granulocytes, monocytes, dendritic cells and platelets
43
Myeloid cell are mostly innate or adaptive
Innate immune cells
44
What are lymphoid made up of
B and T lymphocytes
45
WhT are granulocytes
Cells with lots of granules
46
What do granulocytes do
They circulate in the blood and can move into tissue during inflammation