In a patient who has a significantly high ANA titre, which autoantibody would you test for next?
Which CTD is this antibody associated with?
Which connective tissue disease are Anti-Ro and Anti-La associated with?
Which connective tissue disease is Anti-Jo1 associated with?
Which connective tissue disease is Anti-centromere antibody associated with?
Limited systemic sclerosis
Complication: pulmonary hypertension
Which connective tissue disease is Anti-Scl70 antibody associated with?
Diffuse systemic sclerosis
Complication: pulmonary fibrosis
What are the CREST symptoms of limited systemic sclerosis?
Which markers are used in the diagnosis of rheumatoid arthritis?
Inflammatory markers e.g CRP, PV
Name three small vessel vasculitidies.
Granulomatosis with polyangiitis (formerly Wegener's)
Eosinophilic granulomatosis with polyangiits (formely Churg-Strauss)
Which autoantibodies are associated with
a) Microscopy polyangiitis