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Flashcards in Immunology and Serology Deck (67)
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1

The study of the body's mechanisms that discriminate between self and nonself as well as eliminate non-self components such as infectious agents

Immunology

2

2 main categories of immunology

innate and acquired

3

Non-specific immune system

Innate

4

Specific immune system

Acquired

5

AKA passive immunity
Reacts quickly, but has no memory
Born with this immunity

Innate

6

Foreign substance produced by a pathogen

Antigen

7

A microorganism that can cause disease
Parasites, viruses, bacteria, etc

Pathogen

8

Anatomical barriers, inflammation, and resident flora are examples of

Innate immunity

9

What is the function of resident flora?

Prevents colonization of new microorganisms through microbial antagonism

10

Increase blood flow to a specific area which moves WBCs to affected area

Inflammation

11

Cellular components of innate defenses

1. Neutrophils
2. Macrophages
3. Natural Killer and Lymphokine Killer Cells
4. Eosinophils

12

Travel through the bloodstream and permeates the blood vessel at the site of inflammation to fight infections

Neutrophils

13

Kill viruses

Natural killers
AKA NK cells

14

Kill tumors

Lymphokine killers
aka LAK cells

15

Kill parasites

Eosinophils

16

Recognizes pathogens (has memory)
Able to tell the difference between 'foreign' and 'self' cells
MUST have previous exposure to an antigen

Acquired Immunity
AKA adaptive immunity

17

2 types of acquired immunity

Humoral and cell mediated

18

Immunity within fluids
Can be active or passive
AKA antibody-mediated immune response

Humoral

19

Body produces an antibody after exposure to a foreign antigen artificially or naturally

Active Humoral immunity

20

Passage of an antibody from one animal to another
Ex: colostrum

Passive humoral

21

Generated by the immune system in response to an antigen to defend an animal against a variety of microbes like bacteria, viruses, and protozoa
Consists of 2 polypeptide chairs configured in a Y shape

Antibodies

22

Antibodies are AKA

immunoglobulins

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Imminuglobulins are

proteins

24

Antibodies are produced by

B Cells

25

5 Classes of antibodies

1. IgG
2. IgA
3. IgM
4. IgD
5. IgE

26

First antibody to respond to an antigen
Largest antibody
Only in serum
Clumps microorganisms to help with cell lysis
Activates the compliment system

IgM

27

Most abundant antibody
Found in serum and colostrum
Activates compliment system
Stimulates phagocytic cells
Increases as IgM increases

IgG

28

Least common antibody
Binds to basophils and mast cells
Involved in allergic and parasitic infections by activating histamine secretion to boost inflammation

IgE

29

Second most common antibody
Involved in a great deal of bodily secretions

IgA

30

4th most common antibody
Low numbers in serum
Activate and suppress lymphocyte activity
Found in abundance on the surface of B cells

IgD