IMMUNOLOGY/SEROLOGY Flashcards
- The normal CD4-CD8 ratio in healthy individual is :. In person infected with AIDS, the CD4-CD8 ratio is ?
a. 4:1
b. 3:1
c. 1:2
d. 5:1
e. 0.5:1
e. 0.5:1
- A confirmatory or diagnostic test for HIV infection is?
a. Radioimmune assay
b. Enzyme linked immunosorbent assay
c. Ouchterlony
d. Latex agglutination assay
e. Western blot assay
e. Western blot assay
- The immunologic abnormalities in AIDS include
a. An absence of delayed hypersensitivity
b. Lymphopenia due to CD4 T cells deficiency
c. Reversal of the usual 2:1 ratio of CD4/CD8 blood lymphocytes.
d. Depressed lymphocytes response to mitogens
e. All of the above
e. All of the above
- IgE is produced by
a. Basophils
b. Plasma cells
c. T lymphocytes
d. Eosinophils
e. Mast cells
b. Plasma cells
- In a typical complement fixation test, complement is bound to
a. Free hemolysin
b. erythrocytes
c. Antigen-antibody complex
d. Free antigen
e. Free antibody
c. Antigen-antibody complex
- The method of choice for measuring total Ige in serum is
a. Radial immunodiffusion
b. Radioimmunoassay
c. Indirect immunoflourescence
d. Serum protein electrophoresis
e. Countercurrent electrophoresis
b. Radioimmunoassay
- Grossly elevated serum levels of Ige can be found in
a. Tuberculosis
b. Leprosy
c. AIDS
d. Parasitism
e. Syphylis
d. Parasitism
- Which of the following is found in the milk of lactating women?
a. IgA
b. IgM
c. IgG
d. IgD
e. IgE
a. IgA
- HIV-1 is transmitted via
a. Swimming pools
b. Kissing
c. Sharing of untensils and tootbrush
d. Infected body fluids
e. All of the above
d. Infected body fluids
- Which of the following inhibits viral replication?
a. interleukin-B
b. Interleukin-3
c. Interleukin-4
d. Tumor necrosis factor
e. All of the above
e. All of the above
- The HLA complex is primarily located on
a. Chromosome 3
b. Chromosome 6
c. Chromosome 9
d. X-chromosome
e. Y-chromosome
b. Chromosome 6
- A lymphokine is
a. A soluble mediator produced by lymphocytes
b. An antibody that reacts with lymphocytes
c. A soluble mediator produced by plasma cells
d. A soluble mediator produced by granulocytes
e. None of the above
a. A soluble mediator produced by lymphocytes
- For a substance to be antigenic, it must
a. Be recognized as non-self
b. Be less than 5000 molecular weight
c. Be a linear molecule
d. Be a lipid
e. All of the above
a. Be recognized as non-self
- All immunoglobulins have the same basic structure which consist of
a. Four heavy chains
b. Four light chains
c. Four heavy chains and 4 light chains
d. 2 heavy chains and 2 light chains
e. 2 heavy chains and 4 light chains
d. 2 heavy chains and 2 light chains
- The VDRL Test for syphilis is classified as
a. Agglutination reaction
b. Hemagglutination reaction
c. Flocculation reaction
d. Precipitation reaction
e. Hemolysin reaction
c. Flocculation reaction
- The rapid plasma reagin (RPR) for syphilis does not need to be read
microphysicallly beacause the antigen is
a. Cardiolipin
b. Particulate
c. Complexed to latex
d. Complexed to charcoal
e. Incativated bacterial cells
d. Complexed to charcoal
- Which of the following statements about the test for C-reactive protein (CPR) is
true?
a. It is diagnostics for rheumatic fever
b. It measures patient antibody
c. The antigen used is particulate
d. The antibody used may be absorbed to latex beads
e. All of the above
d. The antibody used may be absorbed to latex beads
- The major class of Immunoglobulin (Ig) found in adult human serum is
a. IgA
b. IgD
c. IgE
d. IgG
e. IgM
d. IgG
- The type of immunity that follows injection of an antigen is
a. Adaptive
b. Active
c. Passive
d. Innate
e. complementary
b. Active
- The Type of immunity that follows injection of antibodies synthesized to another individual or animal is?
a. Adaptive
b. Active
c. Passive
d. Innate
e. complementary
c. Passive
- The strength with which a multivalent antibody binds a multivalent antigen is
termed.
a. Specificity
b. Affinity
c. Avidity
d. Valence
e. None of the above
c. Avidity
- Antibodies arise from
a. Monocyte
b. Plasma cells
c. Metarubricytes
d. Promyelocytes
e. Red cells
b. Plasma cells
- Phagocytosis by reticuloendothelial cells is enhanced by
a. Hemolysins
b. Opsonins
c. Specific anti-toxins
d. Neutralizing antibodies
e. None of the above
b. Opsonins
- The Well-felix reaction is used for laboratory diagnosis of
a. Mycotic disease
b. Bacterial disease
c. Allergic condition
d. Rickettsial antibodies
e. None of the above
d. Rickettsial antibodies