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Flashcards in Immunosuppresive Drugs Deck (8)
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1

What do steroids make worse? X5

HTN
DM
TB
Osteoporosis
Chicken pox

2

When is best time to give steroids

The morning and alternate days if possible

3

What drugs should be avoided when on steroids?

NSAIDs
Aspirin
Ibuprofen
Because increase risk of DU

4

What do you need to give if long term use

Bisphosphonates
Calcium and vitamin D
Prevent osteoporosis

5

What can't you give Azathioprine with?

Allopurinol because azothioprine is metabolised by Xanthine Oxidase - which is inhibited by allopurinol

6

Main side effect of ciclosporin

Nephrotoxicity

7

Side effect of cyclophosphamide

Marrow suppression
Nausea
Infertility
Teratogenic

8

When is immunosuppression used?

Leukaemia+Cancer
Organ and marrow transplant
RA, psoriasis, SLE, vasculitis
Chronic hepatitis
Asthma
IBD