Immunosuppresive Drugs Flashcards
(8 cards)
1
Q
What do steroids make worse? X5
A
HTN DM TB Osteoporosis Chicken pox
2
Q
When is best time to give steroids
A
The morning and alternate days if possible
3
Q
What drugs should be avoided when on steroids?
A
NSAIDs
Aspirin
Ibuprofen
Because increase risk of DU
4
Q
What do you need to give if long term use
A
Bisphosphonates
Calcium and vitamin D
Prevent osteoporosis
5
Q
What can’t you give Azathioprine with?
A
Allopurinol because azothioprine is metabolised by Xanthine Oxidase - which is inhibited by allopurinol
6
Q
Main side effect of ciclosporin
A
Nephrotoxicity
7
Q
Side effect of cyclophosphamide
A
Marrow suppression
Nausea
Infertility
Teratogenic
8
Q
When is immunosuppression used?
A
Leukaemia+Cancer Organ and marrow transplant RA, psoriasis, SLE, vasculitis Chronic hepatitis Asthma IBD
