Inclusions/cells/hard to pronounce names

Question 1

Councilman (acidophil) bodies

Answer 1

Viral hepatitis

Question 2

Mallory-Denk bodies

Answer 2

• Alcoholic steatohepatitis

- Primary Biliary Cirrhosis (AMA +)

Question 3

Chicken-wire fence pattern

Answer 3

Steatofibrosis

Question 4

Hemosiderin deposition

Answer 4

Hemochromatosis

Triad:

1. Micronodular cirrhosis
2. DM
3. Abnormal/skin pigmentation

Question 5

Kayser-Fleisher ring (corneal limbus)

Answer 5

Wilson Disease
- WOW MADAMING COPPER

Tx: D-penicillamine, zinc, liver transplant

Question 6

Rokitansky-Aschoff sinues

Answer 6

Chronic cholecystitis

Question 7

Wire-loop appearance

Answer 7

Type III Focal Lupus Nephritis

• <50% of glomeruli on LM
• subENDOthelial deposits on IF (same with Type IV - diffuse)

Type V Membranous

• LM: diffuse capillary thickening
• IF: SubEPITHELIAL deposits

Question 8

Tram-track appearance on LM

Answer 8

Membranoproliferative glomerulonephritis (MPGN)

Type I
- granular C3 WITH IgG and C1q and C4

Type II
- linear C3 WITHOUT IgG and complements

Question 9

Basket-weave appearance on EM

Answer 9

Hereditary nephritis

- defective assembly of Type IV collagen

Question 10

Michaelis-Gutmann bodies

Answer 10

Malakoplakia

• defect in phagocyte function
• E. coli and Proteus UTI

Question 11

Orphan Annie Nuclei

Answer 11

Papillary Thyroid CA

• most common thyroid CA
• non-encapsulted
• lymphatic spread
• better prognosis than follicar CA
• Psammoma bodies

Question 12

Indian file configuration and signet ring cell carcinoma

Answer 12

Invasive lobular carcinoma of the breast

• (-) e-cadherin
• bilateral, multifocal, multicentric