Skin Pathology Flashcards
(8 cards)
1
Q
Most important risk factor for melanoma
A
Sun exposure
2
Q
Melanocytes are derived from ___________________ cells
A
Neural crest
3
Q
Epidermal and superficial dermis involvement
Superficial spreading
No metastatic potential
More favorable
A
Radial Growth Melanoma
4
Q
Involvement: epidermis, dermis and other structures
Nodular
Has metastatic potential
Less favorable
A
Vertical Growth melanoma
5
Q
Clinical aspects of melanoma
A
ABCDE
- Asymmetry
- irregular Borders
- variegated Color
- increasing Diameter
- Evolution
6
Q
MELANOMA
(+) or (-)?
1. S - 100
2. HMB - 45
A
Both positive
- S - 100 - neural crest cell marker
- HMB - 45 - melanocyte marker
7
Q
Leser-Trélat sign
- rapid increase in number
A
Seborrheic Keratoses
8
Q
Small keratin-filled cysts
Horn cysts
A
Seborrheic keratoses