Skin Pathology Flashcards

(8 cards)

1
Q

Most important risk factor for melanoma

A

Sun exposure

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2
Q

Melanocytes are derived from ___________________ cells

A

Neural crest

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3
Q

Epidermal and superficial dermis involvement
Superficial spreading
No metastatic potential
More favorable

A

Radial Growth Melanoma

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4
Q

Involvement: epidermis, dermis and other structures
Nodular
Has metastatic potential
Less favorable

A

Vertical Growth melanoma

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5
Q

Clinical aspects of melanoma

A

ABCDE

  • Asymmetry
  • irregular Borders
  • variegated Color
  • increasing Diameter
  • Evolution
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6
Q

MELANOMA
(+) or (-)?
1. S - 100
2. HMB - 45

A

Both positive

  1. S - 100 - neural crest cell marker
  2. HMB - 45 - melanocyte marker
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7
Q

Leser-Trélat sign

- rapid increase in number

A

Seborrheic Keratoses

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8
Q

Small keratin-filled cysts

Horn cysts

A

Seborrheic keratoses

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