Infection

Question 1

Which vaccines tend to be safe in immunocompromised individuals?

Answer 1

All except live attenuated

Question 2

Give examples of inactivated pathogen vaccines.

Answer 2

Polio, Flu, Hep A, rabies

Question 3

Give examples of subunit/conjugate vaccines.

Answer 3

Pneumococcus, Meningococcus, Hep B, Pertussis, HiB, HPV, shingles

Question 4

Give examples of live attenuated vaccines.

Answer 4

MMR, BCG, Chickenpox, nasal flu, rotavirus

Question 5

Give examples of toxin vaccines.

Answer 5

Diphtheria and tetanus

Question 6

Which immunisations are in the 6-in-1 vaccine?

Answer 6

Dip/Tet/Polio/Pertussis/HiB/HepB

Question 7

Which vaccines are given at 8 weeks?

Answer 7

6-in-1
Men B
Rotavirus

Question 8

Which vaccines are given at 12 weeks?

Answer 8

6-in-1
Pneumococcal
Rotavirus

Question 9

Which vaccines are given at 16 weeks?

Answer 9

6-in-1
Men B

Question 10

Which vaccines are given at one year of age?

Answer 10

2-in-1 (HiB/MenC)
Pneumococcal
MMR
Men B

Question 11

What is the vaccine schedule for nasal flu vaccine?

Answer 11

Annually aged 2-8

Question 12

Which vaccines are given at 3y 4m?

Answer 12

4-in-1 (Dip/Tet/Per/Polio)
MMR

Question 13

At what age is the HPV vaccine given?

Answer 13

12-13 years

Question 14

Which vaccines are given aged 14?

Answer 14

3-in-1 (Tet/Dip/Polio)
MenACWY

Question 15

At what ages is MMR vaccine offered?

Answer 15

1 year and 3y 4m

Question 16

Which children may be offered BCG vaccination?

Answer 16

From high-risk area or close contact

Question 17

What is the isolation period for pertussis?

Answer 17

Notifiable disease
School exclusion 48 hours after antibiotic dose or 21 days if not treated

Question 18

Which organism causes epiglottitis?

Answer 18

HiB

Question 19

What is the school exclusion rules for hand, foot and mouth?

Answer 19

until apyrexial 24h and all blisters healed

Question 20

What are the school exclusion rules for scarlet fever?

Answer 20

24 hours after first antibiotic dose

Question 21

What are the school exclusion rules for slapped cheek?

Answer 21

No exclusion required

Question 22

What are the school exclusion rules for measles?

Answer 22

at least 4 full days from when the rash first appears

Question 23

Flu-like symptoms
Post-aur & sub-occpital lymphadenopathy
Maculopapular rash
suggests…

Answer 23

Rubella

Question 24

What is the school exclusion advice for chickenpox?

Answer 24

until all of their blisters have crusted over

Question 25

What is the school exclusion period for impetigo?

Answer 25

until lesions are crusted and healed, or 48 hours after commencing antibiotic treatment

Question 26

Rubeola is also known as...

Answer 26

Measles

Question 27

Type 1 reactions are mediated by...

Answer 27

IgE

Question 28

Give examples of Type II hypersensitivity reactions.

Answer 28

Haemolytic anaemia Goodpasture's

Question 29

Type II hypersensitivity reactions are mediated by...

Answer 29

IgM or IgG

Question 30

Premature babies should start their immunisation schedule according to...

Answer 30

their chronological age

Question 31

Type III hypersensitivity reactions are mediated by...

Answer 31

Antigen-antibody immune complexes

Question 32

Type IV hypersensitivity reactions are mediated by...

Answer 32

T-cells

Question 33

Give an example of a type IV hypersensitivity reaction.

Answer 33

Contact dermatitis

Question 34

How does IgA deficiency tend to present?

Answer 34

Recurrent sinopulmonary infections

Question 35

Gonococcal infection is usually resistant to...

Answer 35

tetracyclines

Question 36

Which organism is most commonly implicated in nec fasc?

Answer 36

Group A strep

Question 37

What is the most useful initial investigation in suspected malaria?

Answer 37

Blood film for malarial parasites

Question 38

What is the management for TB meningitis?

Answer 38

12 months anti-TB drugs with steroid cover initially

Question 39

What is the most common causative agent of croup?

Answer 39

Parainfluenza 1

Question 40

Which congenital infection is associated with cerebral calification, chlorioretinitis and hydrocephalus?

Answer 40

Toxoplasma

Question 41

Which congenital infection is associated with sensironeural deafness, cataracts and congenital HD?

Answer 41

Rubella

Question 42

What is the most common intrapartum infection?

Answer 42

CMV

Question 43

Which congenital infection is associated with sensironeural deafness, growth retardation and purpuric skin lesions?

Answer 43

CMV

Question 44

What is the recommended prophylaxis for meningitis case contacts?

Answer 44

Single dose ceftriaxone, ciprofloxacin or azithromycin

Question 45

Which infection is associated with flooding and natural disasters?

Answer 45

Leptospirosis

Question 46

HBsAg suggests...

Answer 46

Active Hep B infection (acute or chronic)

Question 47

Presence of which antigen suggests current Hep B infection?

Answer 47

HBsAg

Question 48

Anti-HBsAg suggests...

Answer 48

Immunisation or cleared infection

Question 49

Anti-HBc IgM suggests...

Answer 49

Recent Hep B infection

Question 50

Anti-HBc IgG suggests...

Answer 50

Resolved or chronic infection

Question 51

Anti-HBe suggests...

Answer 51

Acquired, natural immunity

Question 52

Which organism species is associated with pet reptiles?

Answer 52

Salmonella spp.

Question 53

What is Palivizumab?

Answer 53

Humanised monoclonal RSV antibody

Question 54

Which children are eligible for monthly Palivizumab during RSV season?

Answer 54

Babies born before 35/40 who are < 6 months at start of RSV season Children < 2 with haemodynamically significant CHD or bronchopulmonary dysplasia (treated past 6 months)

Question 55

What is the most common vector for leishmaniasis?

Answer 55

Sandfly

Question 56

Parasitic infection causing chronic diarrhoea...

Answer 56

Giardia lamblia

Question 57

What kind of organism is diptheria?

Answer 57

Gram positive bacillus

Question 58

Which cell are primarily infected by EBV?

Answer 58

B lymphocytes

Question 59

What is the vector of Lyme disease?

Answer 59

Ixodes tick

Question 60

What is the mainstay of treatment in chronic granulomatous disease?

Answer 60

Prophylactic antibiotics

Question 61

At what gestational exposure is congenital rubella syndrome possible?

Answer 61

< 16 weeks