Infections in Pregnancy Flashcards

1
Q

How does fetus acquire syphilis x2

A

Vertical transmission
Transplacental

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2
Q

Adverse effects of congenital syphilis x3

A

Miscarriage
Preterm birth
Perinatal death

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3
Q

Neonatal features of congenital syphilis x5

A

Sabre shins
Saddle nose
Mulberry molars
Hutchinson’s teeth
Eighth nerve deafness

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4
Q

2 specific syphilis tests

A

FTA abs tests
TPI- T.pallidum immobilization test

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5
Q

Medical management of syphilis, dosing and duration

A

Benzyl penicillin 2.4MU IM once weekly, 3 doses

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6
Q

Maternal complications of Group B strep x3

A

Preterm labour
Prolonged ROM
Intrapartum fever

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7
Q

Medical management of group B strep x2 + dosing, timing

A

Ampicilin 2g stat, 1g 4 hourly
Benzyl penicillin 3g stat, 1,5 hourly

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8
Q

Congenital anomalies of rubella x5

A

Cataract
Glaucoma
Deafness
Heart disease
Microcephaly

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9
Q

Fetal manifestations of CMV x3

A

IUGR
Microcephaly
Chorioretinitis

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10
Q

Medical management of CMV

A

Ganciclovir

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11
Q

Which HSV causes neonatal infections

A

HSV2

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12
Q

Fetal manifestation of HSV x4

A

IUGR
Prematurity
Hydrocephalus
Microcephaly

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13
Q

Indications for CS in HSV x2

A

Primary attack within 6weeks
Mother with genital lesions

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14
Q

Methods of transmission of varicella zoster virus x3

A

Direct contact with vesicles
Air borne transmission
Infected secretions from nasopharynx

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15
Q

How vesicles appear in VZV x4

A

Macules> papules > vesicles > crusted papules

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16
Q

Maternal complications of VZV x5

A

Varicella pneumonia
Adrenal insufficiency
Glomerulonephritis
Encephalitis
Arthritis

17
Q

USS findings suggestive of congenital varicella syndrome x5

A

IUGR
Hydrops
Microcephaly
Cardiac malformations
Limb deformities

18
Q

Management of Varicella ZV infection

A

Acyclovir 8000mg PO x5/7
Postpose delivery until a week after rash onset

19
Q

Management of chronic hepatitis

A

Lamivudine 100mg OD

20
Q

Factors affecting initiation of hep b treatment x4

A

Presence of cirrhosis
HBe antigen
HBe antibodies
ALT > 2xupper limit

21
Q

Prevention of neonatal hep b infection x2

A

Hep b immunoglobulin
Hep b vaccine

22
Q

Purpose of cotrimoxazole in HIV positive women

A

Infection prevention, malaria prophylaxis

23
Q

Medical management of baby born to HIV mother x2

A

Nevirapine syrup up to 6wks
Cotrimoxazole from 6wks+

24
Q

Toxoplasmosis triad

A

Chorioretinits
Hydrocephalus
Toxoplasmosis

25
Q

Management of toxoplasmosis x3

A

Spiramycin
Sulfadiazine
Pyrimethamine

26
Q

Describe parameters for UTI x2

A

> 100 000 organisms/ml if asymptomatic
100 organisms/ml with pyuria if symptomatic

27
Q

Prophylaxis for UTI x2

A

Nitrofurantoin
Cephalexin