Maternal adaptation Flashcards

1
Q

State which hormone is responsible hypertrophy(1) and hyperplasia of the uterus (1)

A

Hypertrophy of muscle fibers- estrogen
Hyperplasia of uterine cells - progesterone

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Describe Goodell’s sign, what causes it and when it is seen

A

Softening of the cervix due to increased vascularization from hypertrophy and engorgement of blood vessels below uterus
From week 4 and 8 approximately week 6

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Describe Chadwick’s sign, what causes it and when it is seen

A

It is a bluish discoloration of the mucous membranes of the cervix, vagina and vulva caused by venous congestion as a result of increased blood flow
4-8 Weeks

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Describe hegar’s sign, what causes it and when its seen

A

Compressibility and softening of the cervical isthmus
Caused by increased blood flow, estrogen and progesterone
4-12 weeks

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Function of progesterone x2

A

Raise body temperature
Causes smooth muscle relaxation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What membrane produces HCG and its function

A

Produced by syncytiotrophoblast and stimulates corpus luteum to produces progesterone

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What stimulates the thyroid binding globulin and where is it produced

A

Stimulated by high estrogen levels and produced by hepatic cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Function of T4 thyroid hormone

A

Fetal neural development

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Where is corticotropin releasing hormone produced and its function

A

By placenta
Potentiates the action of prostaglandins and oxytocin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Function of estrogen during labour x2

A

Softening and ripening the cervix

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Hormones produced by fetus in utero that help in labour x2

A

Pituitary produces oxytocin
Adrenal glands produce cortisol which converts progesterone to estrogen which promotes cervical ripening

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Frequency of vaginal exams during latent and active phase of labour x2

A

Once every 6 hours in latent and once every 4 hours in active

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Complications of labour x5

A

Pain
Perineal tears
Excessive bleeding
Fetal distress
Retained placenta

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Define uterine inversion

A

Placenta fails to separate from uterus hence it pulls it inside out as it exits

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

4 changes to the breast

A

Nipple becomes dark and large
Montgometry glands more prominent
Engorgement and dilation of superficial veins
Secretion by 8 weeks

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Uterus position at term x2

A

Dextrorotation
Dextrodeviation

17
Q

3 cervical changes

A

Softens
Proliferation of glands
Formation of mucus plug

18
Q

Define Jacquemier’s sign and what causes it

A

Bluish discoloration of the vagina caused by increased blood supply in the venous plexus

19
Q

4 categories of maternal adaptation

A
  1. Increased precursors for hormone production
  2. Improved transport capacity
  3. Exchange of nutrients and oxygen
  4. Removal of additional waste products by peripheral vasodilation
20
Q

What causes the fall in BP x2

A

Decreased peripheral resistance
Formation of AV shunts in placenta

21
Q

Causes of dyspnea in pregnancy x3

A

Reduced pCO2
Increased TV
Reduced TLC

22
Q

Effects of bladder pressure from uterus x4

A

Increased micturition
Urinary stasis
Stress incontinence
Hydronephrosis and hydroureter

23
Q

True or false. Free T3 &T4 levels change during pregnancy

A

False

24
Q

3 anti insulin hormones

A

Prolactin, lactogen, cortisol

25
Q

What causes ketoacidosis in pregnancy

A

Lipolysis since maternal source of energy shifts from glucose to lipids

26
Q

Why is pregnancy a hypercoagulable state x4

A

Increased clotting factors
Decreased fibrinolytic agents
Venous stasis
Endothelial injury

27
Q

GIT changes x5

A

Relaxation of GIT muscles
Increased transit time
Constipation
Hemorrhoids
Gums- soft and easily bleed

28
Q

Musculoskeletal complications of pregnancy x2

A

Lumbar lordoisis
Carpal tunnel syndrome

29
Q

Effect of relaxin and progesterone on pelvic ligaments x2

A

Relaxation and pain (pelvic girdle and coccygeal)

30
Q

Effect of estrogen in pregnancy x3

A

Induce growth of fetal organs
Stimulate maternal tissue growth
Suppress FSH and LH