Infectious Disease

Question 1

Tingling/pain then painful blisters on R trunk. Dx?

Answer 1

Shingles

Question 2

List 2 complications of shingles

Answer 2

Post-herpetic neuralgia

Ocular disease

Question 3

What is Tx for shingles?

Answer 3

Oral acyclovir

Question 4

How does shingles Tx differ in immunocompromised pt?

Answer 4

High dose IV acyclovir

Question 5

Painful rash on penis with fever and myalgia. Dx?

Answer 5

Herpes

Question 6

What is Tx for Herpes?

Answer 6

Oral acyclovir

Question 7

Man with purulent urethral discharge. Dysuria. Dx?

Answer 7

Gonorrhoea

Question 8

What are Sx of gonorrhoea in women?

Answer 8

Asymptomatic

OR vaginal discharge / pelvic pain / dysuria

Question 9

What are the usual Sx of chlamydia?

Answer 9

Nothing - asymptomatic

Question 10

Painless hard ulcer on penis. Dx?

Answer 10

Primary syphillis

Question 11

What organism causes primary syphillis?

Answer 11

Treponema pallidum

Question 12

How long does syphillis take to develop from contact?

Answer 12

3 weeks

Question 13

How long does secondary syphillis take to develop?

Answer 13

4-8 weeks

Question 14

What are Sx of secondary syphillis?

Answer 14

Lymphadenopathy, malaise, rash

Question 15

What is Tx of primary syphillis?

Answer 15

Procaine penecillin

Question 16

What kind of ABx is ciprafloxacin?

Answer 16

Quinolone

Question 17

Which type of hepatitis is most common worldwide?

Answer 17

Hep A

Question 18

Fever, malaise, anorexia, nausea. Then jaundice. Dx?

Answer 18

Hep A

Question 19

How are Hep A / B / C transmitted?

Answer 19

A = faecal-oral

B and C = IV / sexual

Question 20

How do Hep C patients present?

Answer 20

Chronic - with liver cirrhosis

Question 21

Fever, headache, vomitting, diarrhoea. Dx?

Answer 21

Malaria

Question 22

What is Tx of Hep A?

Answer 22

Conservative - self limiting disease

Question 23

What is Tx for Hep C?

Answer 23

Pegylated Interferon alpha & ribavarin

Question 24

What is Tx for malaria?

Answer 24

Chloroquine

Question 25

Fever, anorexia, sore throat. Lymphadenopathy. Inflammed tonsils. Dx?

Answer 25

EBV

Question 26

List complications of infectious mononucleosis

Answer 26

Meningitis Encephalitis GBS

Question 27

How is PC of strep sore throat different from EBV?

Answer 27

Strep has NO widespread lymphadenopathy

Question 28

What is immediate Mx of bacterial meningitis?

Answer 28

1.2mg IM benzylpenicillin | Immediate hospital transfer

Question 29

Koplik spots, fever, cough, coryza. Dx?

Answer 29

Measles

Question 30

Parotid swelling w fever, malaise, lethargy. Dx?

Answer 30

Mumps

Question 31

What are Koplik spots?

Answer 31

Clustered grey lesions in buccal mucosa adjacent to second molar

Question 32

Fever, headache, expanding red rash on thigh. Prev camping trip. Dx?

Answer 32

Lyme disease

Question 33

What is Lyme disease?

Answer 33

Tick spread infection

Question 34

How do you confirm TB diagnosis?

Answer 34

Ziehl-Nielsen Stain

Question 35

Name the 2 main causative organisms of bacterial meningitis

Answer 35

Neisseria meningitides | Strep pneumoniae

Question 36

Non blanching rash with meningism Sx. Causative organism?

Answer 36

ALWAYS neisseria meningitides

Question 37

Erythematous ulcer on forearm of man who spent few weeks in South America. Dx?

Answer 37

Leishmaniasis

Question 38

What transmits Leishmaniasis ?

Answer 38

Sand fly

Question 39

What transmits schistosomiasis?

Answer 39

Fluke worms in water

Question 40

What confirms the disease of Leishmaniasis?

Answer 40

Leishamn-Donovan bodies in bone marrow/spleen/lymph nodes/skin

Question 41

Itchy rash on feet with fever, malaise, myalgia and cough. Dx?

Answer 41

Schistosomiasis

Question 42

Features of Schistosomiasis O/E?

Answer 42

Hepatosplenomegaly Fever Eosinophilia

Question 43

6 week Hx of diarrhoea, abdo pain, nausea and pale stool. Dx?

Answer 43

Giardia

Question 44

Tx of giardia?

Answer 44

Metronidazole

Question 45

1 week Hx of fever, headache, malaise and cough. O/E: Patchy maculopapular rash on trunk + splenomegaly. Leukopenia. Dx?

Answer 45

Typhoid

Question 46

Flu like prodrome. Lockjaw. Dx?

Answer 46

Tetanus

Question 47

What causes tetanus?

Answer 47

Infected wounds - clostridium tetani

Question 48

What is Tx of MRSA?

Answer 48

Isolation and IV vancomycin

Question 49

What is the most common causative organism of endocarditis due to dental procedures?

Answer 49

Strep viridans

Question 50

What is the most common causative organism of IE in IVDU/prosthetic heart valve its?

Answer 50

Staph aureus

Question 51

Itchy rash on web spaces between fingers and toes. Dx?

Answer 51

Scabies

Question 52

What is the most common cause of septic arthritis in young men?

Answer 52

Neisseria gonorrhoea

Question 53

What is the most common cause of septic arthritis in children?

Answer 53

Haemophilius influenzae

Question 54

What is the most common cause of septic arthritis in old men?

Answer 54

Staph aureus

Question 55

Dry cough, exertional dyspnoea, fever and malaise. PMH: AIDS. Dx?

Answer 55

Pneumocystis jiroveci

Question 56

Fungal infection of oesophagus in HIV+ patient. Organism?

Answer 56

Candida albicans

Question 57

Tx of candida albicans?

Answer 57

Floconazole

Question 58

What organism causes meningitis in HIV+ patients?

Answer 58

Cryptococcus neoformans

Question 59

Pigmented, well defined papules in HIV+ patient. Dx?

Answer 59

Kaposi sarcoma

Question 60

What virus is Kaposi's sarcoma associated with?

Answer 60

HHV 8

Question 61

Loss of visual acuity, floaters and headache in HIV+ patient. Haemorrhages and exudates on fundoscopy. Dx?

Answer 61

CMV retinitis

Question 62

Encephalitis with multiple ring enhancing lesions on CT. PMH: HIV+. Dx?

Answer 62

Toxoplasmosis