Infectious/Inflammatory Conditions Flashcards Preview

Nephrology > Infectious/Inflammatory Conditions > Flashcards

Flashcards in Infectious/Inflammatory Conditions Deck (6)
Loading flashcards...

What is cystitis?

Acute cystitis is an infection of the bladder. The route of infection is typically ascending from the urethra.


What is the most common cause of cystitis?

Cystitis is most commonly due to the coliform bacteria (especially E. Coli) and occasionally to gram-positive bacteria (enterococci).


What are the signs and symptoms of cystitis?

Irritative voiding symptoms (frequency, urgency and dysuria) and suprapubic discomfort are common. Symptoms may present after intercourse.

Physical exam may elicit suprapubic tenderness but the examination is often unremarkable.


What are the laboratory findings for cystitis?

UA shows pyuria and bacteriuria and varying degrees of hematuria. Urine culture is positive for the offending organism, but colony counts exceeding 10^5 are not essential for diagnosis.


How do we prevent cystitis?

Women who have more than 3 episodes of cystitis per year are considered candidates for prophylactic antibiotic therapy to prevent recurrence after treatment of a UTI. The most common oral agents for prophylaxis are trimethoprim-sulfamethoxazole, nitrofurantoin, and cephalexin.


How do we treat cystitis?

Uncomplicated cystitis in women can be treated with short term anti microbial therapy, which consists of single dose therapy. Cephalexin, Nitrofurantoin and fluoroquinolones are the drugs of choice.