Inflammatory Disorders Flashcards Preview

Week 44: Rash > Inflammatory Disorders > Flashcards

Flashcards in Inflammatory Disorders Deck (19)
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1

Papulosquamous conditions

Psoriasis
Atopic and contact dermatitis
Seborrheic dermatitis
Pityriasis rosea
Lichen planus
Drug eruptions

2

5 cardinal signs of psoriasis

Plaque
Well-circumscribed
Bright red colour
Silvery scale
Symmetric

3

Common places for plaque type psoriasis

Scalp
Elbows
Knees
Palms and soles

4

3 nail signs in psoriasis

Nail pitting
Lifting of the nail plate (onycholysis)
Oil drop sign

5

Types of psoriasis

Plaque type
Guttate variant
Inverse psoriasis
Pustular psoriasis
Erythrodermic psoriasis

6

What type of T cells are involved in
1. Psoriasis
2. Eczema

1. Th1 or Th17
2. Th2

7

Atopic dermatitis

Eczema
Ill defined margins, erythema
Mostly on flexor surfaces
Scale
Can see lichenification

8

Seborrheic dermatitis

Commonly found on the scalp, eyebrows, around the ears, nasolabial folds, and can be on the trunk
Not well demarcated
Fine scale

9

Pityriasis rosea

Always on the trunk where the shirt is
Never involves the face and scalp
Plaques tend to be oval and follow the skin lines
Has Herald's patch (first lesion, largest)
Fine scale within the plaque

10

5 P's of lichen planus

Papules
Polygonal (not true circles)
Purple
Planar (flat topped)
Pruritic (can have excoriation)

11

Most common presentation of a drug eruption

Morbilliform rash
Combo of macules and papules

12

Bullous pemphigoid

Age > 60 years old
Tense bullae
Surrounding erythema
Very itchy
Antibodies are targeting antigens in the basement membrane

13

Pemphigus vulgaris

Age 40-60
Flaccid bullae
Erosions present
Oral mucosa often involved
Higher mortality rate that bullous pemphigoid
Antibodies target antigens in the stratum spinosum
Positive Nikolsky sign (skin will slough if you press on it)

14

Steven Johnson's syndrome

Necrosis of epidermis
Hemorrhagic crusted erosions
Mucosal involvement
Life threatening
Mostly caused by medications
Dark hemorrhagic crust on the lips is very classic

15

Toxic epidermal necrolysis

Necrosis of epidermis
> 30% of body surface area involvement
An extension of Steven Johnson's
High mortality rate (heat loss, blood flow, infection)
Have to be transported to a burn unit

16

6 causes of well defined scaly plaques

Psoriasis
Contact dermatitis
Seborrheic dermatitis
Pityriasis rosea
Lichen planus
Drug eruptions

17

2 causes of poorly defined red scaly plaques

Atopic dermatitis
Other forms of ezcema

18

3 causes of tense bullae

Bullous pemphigoid
Bullous impetigo
Arthropod assault

19

3 causes of flaccid bullae/erosion

Pemphigus vulgaris
Steven Johnson's syndrome
Toxic epidermal necrolysis