Skin Cancer Flashcards Preview

Week 44: Rash > Skin Cancer > Flashcards

Flashcards in Skin Cancer Deck (12)
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1

UVB

Carcinogenic
Causes sunburn
Blocked by glass
Photons absorbed directed by DNA

2

UVA

Carcinogenic
Also involved in tanning and wrinkling
Indirect DNA damage through oxidization

3

2 types of melanin

Eumelanin (brown-black)
Phaeomelanin (red)

4

Basal cell carcinoma

Most common
Locally destructive but not usually metastatic
Translucent, telangectasia, papular, can be ulcerated or eroded

5

4 variants of BCC

Superficial spreading
Nodular
Sclerosing
Pigmented

6

Freckles (ephelids)

Secondary to sun damage
Not precancerous
Fade/get stronger depending on sun exposure

7

Seborrheic keratosis

Some texture to it
"stuck on appearance"
Very common
Not precancer

8

Nevi (moles)

Proliferations of abnormal melanocytes
Most acquired ones are secondary to sun damage

9

ABCDEs of melanoma

Asymmetry
Border irregularity
Colour variation
Diameter (> 6 mm)
Enlarging or evolving

10

Superficial spreading melanoma

Often from atypical nevi
Most common type
Irregular edge, colour variation, quite flat until late, often large

11

Nodular melanoma

No precursor lesion
Usually a black nodule

12

Lentigo maligna melanoma

From lentigo maligna
Often on the face
Very slowly progressive as a large flat patch, then a nodule occurs