Inflammatory myopathies Flashcards Preview

Musculoskeletal/Rheumatic > Inflammatory myopathies > Flashcards

Flashcards in Inflammatory myopathies Deck (10):
1

Rash seen in dermatomyositis

Gottron's sign/papules, rash on knuckles and dorsum of hand, knee/elbow rash, linear erythema, scalp rash, V-like sign, shawl sign, mechanics hands

2

Epidemiology of inflammatory myopathies

Teens or old people

3

DM and PM associated with what condition?

Malignancies - particularly breast CA and adenocarcinoma of lung

4

Immune response in DM and PM

DM involve perimysial areas with CD4 cells and PM/IBM involves endomysial with CD8 T cells

5

Organ involvement in inflammatory myopathies

Proximal muscles weakness that's symmetric, upper 1/3 of esophagus, skin, ILD, arthritis, heart

6

Antibody in inflammatory myopathy

Anti-Jo1; associated with arthritis

7

Inclusion body myositis

Affects men, affects thigh muscle and finger flexors, resistant to steroids

8

Diagnostic features of inflammatory myopathies

Elevated CPK, abnormal EMG

9

Serious complication of giant cell arteritis

Thoracic aortic aneurysms

10

Association of PMR with GCA

1/2 of cases of GCA also have PMR