Influenza Flashcards Preview

Microbiology 39 > Influenza > Flashcards

Flashcards in Influenza Deck (12):
1

Signs and Symptoms for Influenza

-Sudden fever
-Pharyngitis
-Congestion
-Cough
-Tiredness
-Pale
-Muscle ache

2

Causative agents for Influenza

Influenza virus types A and B
-Envelope virus
-RNA virus

3

What are the two main causes for mutations in Influenza?

-Antigenic drift
-Antigenic shift
-^^ cause multiple strains

4

Pathogenesis for Influenza

-Produced immune response to the virus
-Flu patients are susceptible to secondary bacterial infections

5

Epidemiology for Influenza

-Complications in the elderly, children, and those with chronic diseases
-2009 H1N1 variants bound lower in respiratory tract causing massive cytokine storm

6

Diagnosis for Influenza

-Signs and symptoms
-Often diagnostic

7

Treatment for Influenza

-Four drugs approved
-Take during the first 48 hours
-Supportive care
-Antiviral (early on)

8

Prevention for Influenza

-Immunization
-Multivalent vaccine
-IgG/ flu vaccination (works 10%)

9

Pathogenesis and Virulence Factors for Influenza

-Virus binds ciliated cells of the respiratory mucosa
-Severe inflammation, irritation in lungs due to “cytokine storm”

10

Culture for Influenza

-Culture and non-culture based tests
-Rapid influenza tests:
-Immunofluorescence
-PCR
-ELISA
-Viral culture

11

If not treated?

Pneumonia (most likely if really young or really old)

12

Transitions fr Influenza

Transmitted via inhalation of airborne viruses or by self-inoculation

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