inhalation agents, MAC

Question 1

MAC is ___ related to potency

Answer 1

inversely

Question 2

MAC amnesia = __% MAC

Answer 2

25

Question 3

MAC awake = __ %MAC

Answer 3

50

Question 4

MAC intubation = ___% MAC

Answer 4

130

Question 5

MAC BAR = ___% MAC

Answer 5

150

Question 6

what age has the greatest MAC requirement

Answer 6

term infant to 6mo

Question 7

chronic ETOH ___ MAC

Answer 7

increases

Question 8

which electrolyte increases MAC

Answer 8

na - hypernatremia

Question 9

hyper or hypothermia increases MAC?

Answer 9

hyper

Question 10

drugs that increase CNS catecholamines ___ MAC

Answer 10

increase

Question 11

for every 1 degree drop in C in body temp, MAC decreases by ___%

Answer 11

2-5%

Question 12

pregnancy __ MAC

Answer 12

decreases

Question 13

PAo2

Answer 13

38

Question 14

which electrolyte has no effect on MAC

Answer 14

k

Question 15

4 factors that have no effect

Answer 15

thyroid gland dysfunction, duration, gender, CO2 (hypo/hypercarbia)

Question 16

uptake from alveolar space depends on

Answer 16

solubility, cardiac output, and alveolar/venous partial pressure difference

Question 17

the most important single factor in determining speed of induction and the rate of emergence

Answer 17

solubility

Question 18

the lower the blood:gas coefficient the __ solubility

Answer 18

lower

Question 19

the more soluble an agent, the ___ it will be taken up into the pulmonary capillaries and into body tissues

Answer 19

more

Question 20

blood:gas des

Answer 20

.42

Question 21

blood:gas n20

Answer 21

.47

Question 22

blood:gas sevo

Answer 22

.68

Question 23

blood:gas iso

Answer 23

1.4

Question 24

a poorly soluble agent has a ___ inhalation and emergence

Answer 24

faster

Question 25

high cardiac output, ___ rate of rise and induction

Answer 25

slow

Question 26

low cardiac output, ___ induction

Answer 26

fast

Question 27

a large alveolar/venous partial pressure difference with an agent ___ uptake and ___ inhalation

Answer 27

enhances, speeds

Question 28

second gas effect

Answer 28

the ability of a large volume of uptake of a first gas (N2O) to accelerate the rate of rise of the alveolar partial pressure of a concurrently administered companion gas (agent) thus speeding induction

Question 29

diffusion hypoxia

Answer 29

results from the dilution of alveolar 02 concentration by a large amount of N20 "outgasing" or leaving the pulmonary capillary blood at the conclusion of n2o administration

Question 30

inhalation agents __ HPV

Answer 30

inhibit

Question 31

inhalation agents ___ non depolarizing NMB's

Answer 31

potentiate

Question 32

N20 ___ PONV

Answer 32

increases

Question 33

avoid N20 use in

Answer 33

closed gas spaces: PTX, complete bowel obstruction, inner ear, pneumocephalus, air embolism, intraocular bubbles

Question 34

n20 affect on PVR

Answer 34

increases PVR in patients with pre-exisiting pulm htn.

Question 35

n20 and fire

Answer 35

nonflammable but an O2 source and supports combustion

Question 36

N20 inhibits ___ synthesis

Answer 36

methionine. caution in use in pregnancy

Question 37

long term use of n20 leads to

Answer 37

peripheral neuropathy and megaloblastic anemia

Question 38

halothane causes a dose dependent decrease in

Answer 38

contractility

Question 39

halo has ___ preservative

Answer 39

thymol.

Question 40

pretreat children with ___ for vagal stimulation associated with halo

Answer 40

atropine

Question 41

which gas sensitizes the heart to catecholamines, dyrhythmogenic, use epi with caution

Answer 41

halo

Question 42

which gases have a pungent odor

Answer 42

iso/des

Question 43

which gases cause increase in HR esp when rapidly increasing dose

Answer 43

iso/des

Question 44

coronary steal syndrome

Answer 44

iso... normal coronaries dilate and stenotic ones dont so blood is shunted away from diseased vessels

Question 45

which gas is good for inhalation induction

Answer 45

sevo

Question 46

which gas forms compound A

Answer 46

sevo

Question 47

with sevo keep flows at at least

Answer 47

2L/min

Question 48

avoid __ in renal patients

Answer 48

sevo

Question 49

mac of enflurane

Answer 49

1.68

Question 50

mac of halo

Answer 50

.75