Innate immunity 1 Flashcards

(25 cards)

1
Q

continually shed and renewed

A

stratum corneum

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2
Q

components of the stratum corneum

A
dead keratinocytes
keratin
ceramides
free fatty acid
cholesterol
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3
Q

Skin:Bacterial colonization is prevented by other factors

A

Perspiration(sweat)

Sebaceous glands

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4
Q

The respiratory tract is protected from infection by:

A

SILYA EC,ML(gmpro),TRAPPM,Mucocillary escalator
• ciliated epithelial cells
• mucous layer, glycosylated mucous proteins
• trap particulate matter
• mucociliary escalator

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5
Q

Elevator function is decreased by

A

HALO-HALOCOKE=-SO2(co2?)=smoking/cold air
• halothane, cocaine, and sulfur dioxide are toxic to epithelial cells.
• Smoking or inhalation of toxic fumes
• cold or dry air

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6
Q

• inherited syndrome characterized by impaired transport and the abnormal structure of cilia.

A

• Primary ciliary dyskinesia (PCD)

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7
Q

Can survive stomach acid

A

H. pylori

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8
Q

found in the intestine and also toxic to bacteria

A

Bile salts

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9
Q

Acids in the vaginal mucosa are produced by

A

Lactobacilli

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10
Q

risk of vaginal infection is increased by

A

increased urine pH

reduced Lactobacillus population

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11
Q

molecules that are shared by most pathogenic bacteria

and some viruses.

A

Pathogen-associated molecular

patterns (PAMPs)

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12
Q
constituents of microbial cell walls, single-stranded and
double-stranded nucleic acids, or unmethylated
deoxyribonucleic acid (DNA).
A

Pathogen-associated molecular

patterns (PAMPs)

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13
Q

different mechanisms of PAMPS

A
  • Serum complement components
  • Receptors on leukocytes and tissue cells
  • Acute phase proteins
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14
Q

Peptidoglycan

A

DOG(+)

Gram positive bacteria

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15
Q

Lipopolysaccharide

A

POPO(-)

Gram negative bacteria

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16
Q

Lipotechoic acids

A

Tech(+)

Gram positive bacteria

17
Q

Flagellin

A

Flag

bacteria

18
Q

Lipoarabinomannan

A

RAB My Back

Mycobacteria

19
Q

Beta 1,3 glycan

A

Bata 1,3 glycan

Fungi

20
Q

Respiratory synctial virus(RSV)

21
Q

Double stranded RNA

A

Double s

ViruSeS

22
Q

Lipopeptides

A

Popep my co(+)

MYco-plasma

23
Q

Unmethylated CpGDNA

A

DNAsipag
CpGDNA(cytosine phosphate guanine)
Bacteria

24
Q

PROFILIN-LIKE molecules

A

Toxic profile

Toxoplasma

25
PAMPS
Pathogen-associated Molecular patterns