Integument and related structures Flashcards

1
Q

Special features of the integument

A

Pigmentation
Paw pads
Ergots and chestnuts
Planum nasale
Cutaneous pouches in sheep

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2
Q

Functions of the skin

A

Covers and protects
Prevents desiccation
Reduces threat of injury
Assists in maintenance of normal body temperature
Excretes water, salt, organic wastes
Receives and conveys sensory information
Synthesizes vitamin D
Stores nutrients

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3
Q

Skin maintains a suitable internal environment for other body tissues and organs by preventing:

A

Loss of water and electrolytes from the body
Access of external chemicals, micro-organisms and toxins to the body

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4
Q

Epidermis

A

Above the basement membrane
Composed of keratinized stratified squamous epithelial cells
No blood vessels

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5
Q

Dermis

A

Tough layer below
Composed of dense irregular connective tissue
Contains blood vessels
Below is the hypodermis, or subcutaneous layer
Primarily adipose tissue (thermoinsulation and protection against injury)

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6
Q

Keratinocyte

A

Keratin gives skin resiliency and strength
Helps make it waterproof
Majority of skin cells
Produced at basement membrane
Become keratinized, loose nucleus, die (keratinization)
Sloughed at surface

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7
Q

Melanocyte

A

Produces melanin pigment
Processes extend up through the epidermis
Protects against UV light

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8
Q

Langerhans cell

A

Phagocytizes microinvaders

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9
Q

Merkel cell

A

Associated with sensory nerve endings

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10
Q

5 layers of thick skin

A

Stratum corneum = horny layer
Stratum lucidum = clear layer
Stratum granulosum = granular layer
Stratum spinosum = spiny layer
Stratum germinativum = stratum basale = basal layer

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11
Q

Layers of thin skin

A

Stratum corneum
Stratum spinosum
Stratum basale

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12
Q

Thin skin epidermis description

A

Scalelike folds on skin surface
Hair grows out from folds
Tactile elevations = epidermal papillae
A tactile hairs = tylotrich hair grows from each papillae
Sense of touch

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13
Q

Dermis composed of what CT

A

Highly fibrous; dense irregular connective tissue
Collagen, elastic, reticular fibers
Provides strength
Can be tanned to make leather

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14
Q

Component of dermis

A

Hair follicles, nerve endings, glands, smooth muscle, blood vessels, lymphatic channels, fibroblasts, adipocytes, macrophages

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15
Q

Papillary layer of dermis

A

Thin, superficial layer
Lies just below epidermis
Dermal papillae
Looping blood vessels
Nerve endings (pain) and Meissner’s corpuscles (touch)

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16
Q

Hypodermis description

A

Thick layer, below dermis
Allows skin to move freely over underlying structures
Loose layer of areolar tissue containing:
Fibers continuous with dermis
Adipose, blood and lymphatic vessels, nerves
Pacinian corpuscles
Special type of touch receptor for heavy pressure

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16
Q

Reticular layer of the dermis

A

Majority of dermis
Indistinct boundary between papillary layer
Parallel bundles of collagen fibers
Arranged parallel to tension
Skin incisions are made along these lines
Minimizes wound gaping
Speeds healing
Dermal folds or flexure lines e.g. at joints

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17
Q

Pigmentation of the skin

A

All animals have melanocytes
The amount and type (orange/black) of melanin produced is variable
Albinos produce no melanin
Pigment is released in vesicles which are taken up by keratinocytes to give them color
Coat color is the result of the presence or absence of melanin granules in extensions of melanocytes, keratinocytes and hair.
Sun exposure increases melanin synthesis in people

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18
Q

Functions of the paw pad

A

Shock absorbers for the feet
Insulation against heat and cold
Protection against rough surfaces

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19
Q

Foundation of he paw pad

A

A thick layer of fat and CT
Covered by thick epithelium

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20
Q

Layer of paw pads

A

Have the thickest and toughest skin on the body – has all 5 layers
Thick surface layer (stratum corneum) that is rough and in the form of conical papillae
Worn almost smooth on the walking surface

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21
Q

Paw pad glands

A

Has exocrine sweat glands
The only site where most domestic animals sweat
Except horses!

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22
Q

Sites on the paw pad include

A

Carpal: on the caudal surface of the carpus, at the accessory bone
Metacarpal/Metatarsal: main weight bearing foot pad
Digital: one on each toe

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23
Q

Ergots and chestnuts are

A

Dark, horny structures on legs of equine family
Thought to be vestiges of digits

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24
Chestnuts are located
Medial on each leg at carpus and tarsus
25
Ergots are located
Buried in caudal hairs of fetlock
26
Planum nasale
Dorsum of nose in cats, pigs, sheep, dogs Composed of polygonal plates in dogs
27
Planum nasolabial
Extends to lips Muzzle of cows Hairless in cattle
28
Planum Nasale/Nasolabiale
Usually pigmented Aglandular in SA, glandular in sheep and cattle
29
Why do cows lick there nose
Sick cows may stop licking their nose and drool clear mucous from their nose Not necessarily a sign of respiratory disease
30
Cutaneous pouches in sheep are and location
Infoldings of skin Contain fine hair, sebaceous and oil glands Three locations Infraorbital Interdigital Inguinal Fatty yellow secretion dries and sticks to skin
31
PRISH in skin
Pain Itching (licking/chewing/scratching) (pruritus) Reddening Immobility (Loss of function) Alopecia (loss of hair) Thickening (lichenification) Wrinkling Pigmentation (melanosis) Swelling: Edema Heat
32
Functions of hair
Maintenance of body temperature Traps air Dark colors absorb light Protection via camouflage
33
Hair folilicle
Shaft: part of hair visible above skin Root: part of hair below skin Hair follicle: invagination of the epidermis into dermis or hypodermis
34
Hair shaft three layers
Medulla: core of the hair Cortex: hard keratin – thickest layer Cuticle: thin layer of cells on the surface of the hair arranged in shingle-like layers
35
Hair bulb is
deepest part of hair follicle – expanded, knob-like, hollow area
36
Papilla is
mound of dermal cells at the base of the bulb
37
Matrix is
rapidly dividing epithelial cells covering the papilla Nourished by vessels below As cells divide, they push older cells up become keratinized & die become hair
38
Root hair plexus
Web of sensory nerve endings around the root Makes hair sensitive to touch
39
Compound follicles
Multiple hair strands, each with its own follicle, can emerge from a single pore Three follicles group to emerge from same epidermal fold in dogs Can contain a mixture of primary and secondary follicles (see later)
40
Three stages of growth in hair
Anagen: growth Catagen: transition Telogen: resting
41
During telogen what happens
During telogen hair bulb separates from the dermis Hair falls out or is pushed out when new hair growth starts ‘Shedding’ the coat is technically called telogen effluvium Can occur seasonally (photoperiod), due to disease, or through hormonal changes (such as after parturition in bitches (blowing the coat)
42
telogen effluvium
shedding the coat
43
Hair colour is determined by
Pigment in cortex and medulla of hair strand Melanin produced in base of hair follicle Melanin transferred to cortical and medullary cells of hair strand Different colors Quantity of melanin Type of melanin Orange type Black/brown type No melanin = white Melanin production decreases with age
44
Primary hair
guard hairs Straight or arched; thicker and longer than secondary hairs
45
Secondary hair
Softer and shorter than primary hairs Predominant type of hair in wool type coats Wool breeds have many secondary hair follicles
46
Compound hair follicles often have
Long primary guard hair Surrounded by soft wool hairs
47
Tactile hair
Wool breeds have many secondary hair follicles Secondary hair is often waxy (lanolin) Makes it waterproof Used in skin ointments
48
Arrector Pili Muscle
Small, smooth muscle Attached to each hair follicle Innervated by sympathetic nervous system Contraction pulls the hair erect
49
Sweat glands are and do what
Sudoriferous Glands Produce watery, transparent liquid Help cool body through evaporation Found over entire body Only horse produces profuse sweat
50
Two types of sweat glands
Eccrine: empty onto surface of skin Apocrine: empty into hair follicles
51
Sweat glands are and what do they do
Located in dermis Simple or complex alveolar structures Duct empties into hair follicle or directly onto skin Lips, labia vulvae, penis, prepuce, anus, eyelid, ear canal (ear wax) Produce sebum Oily, lipid substance Manufactured and stored by sebaceous glands Sebum forced through duct into hair follicle
52
Sebum does what and is also called
Sebum coats base of hair and surrounding skin Traps moisture Keeps skin and hair soft, pliant, waterproof Reduces risk of infection Sheep sebum is called lanolin
53
Sebaceous glands
Secretion of sebum is hormone sensitive Increased production of sebum at puberty, sebum binds dead skin cells, blocks duct opening. Ducts swell and may rupture – releases bacteria into epidermis and dermis,inflammation and abscess
54
Tail and chin glands
Oval region at dorsal base of tails of dogs and cats, contain: Large sebaceous glands Coarse, oily hairs May have different color Assist animals in identification of one another More noticeable in males Called Stud Tail in cats Also found on chin and lips of cats May develop into cysts
55
Anal sacs
Reservoir for malodorous secretions, similar to those from musk glands Lined with sebaceous and apocrine glands Contents are expressed at: Defecation: marks territory When animal is frightened Location in cats and dogs Connected by single small duct to lateral margin of anus Can become blocked / infected
56
Anal sac disease is
May become impacted or infected – ‘scooting’ Pain and discomfort on sitting Licking and biting at anal area Painful defecation If severe, may swell and rupture and drain pus May be a sign of allergies
57
Treatment for anal sac disease
Express with digital pressure Keep your mouth closed Flush with catheter and warm water +/- disinfecting soap May surgically remove
58
Ruminant hooves
Ruminants have 4 hooves per foot – each covers a digit, but only 2 digits (3rd and 4th) per foot are weight- bearing
59
Bovine hoof
Weight bearing hooves are called medial and lateral claw
60
Hoof wall
Is equivalent to our fingernail Divided into toe, quarters (medial and lateral), and heel regions Thickest at the toe and thinnest at the heel. Hoof wall cross sections Have tiny vertical lines running from coronary band to ground - called horn tubes May have horizontal rings or ridges around hoof – represent different periods of growth due to changes in nutrition or founder Grows continuously from the (corium of the) coronary band down Hoof walls are flexible and expand as weight is born on hoof
61
Corium
like a modified dermis The underlying tissue which is sensitive and vascular. Firmly attached to periosteum of distal phalanx – links bone to hoof wall Lots of blood vessels and nerves Divided into coronary corium (beneath coronary band), perioplic corium (beneath periople), laminar (wall) corium, sole corium (on the sole of the foot), and corium of the frog (above/behind the frog)
62
Periople or Perioptic corium
Narrow region approximately 2-3 cm at proximal border of hoof Epidermal cells here produce the external layer of the hoof wall Corresponds to the cuticle of the fingernail Waterproof and pigmented
63
Coronet or Coronary corium
Wider band distal to periople Cells here produce the middle layer of the hoof wall The hoof grows from the coronary band downward Growth of the hoof is continuous Without trimming the hoof can become so long that it curls upward
64
How the corium and epidermis (hoof wall) attach to each other
Hoof and corium form laminae, which interlock Connect the hoof wall to the corium, which is bound to P3 Laminae permit hoof wall to grow distally by sliding over each other Dermal laminae are sensitive
65
Sole of the horse hoof
Bottom (plantar or palmar) surface of the hoof Protects from injury Concave – not primary weight-bearing area Improves foothold No nerves or vessels superficially White line – indicates junction of the sole and hoof wall
66
Frog of the horse hoof as and functions to
Triangular shaped structure with a central sulcus or cleft Below the frog is a thick pad of fat and fibrous tissue, called the digital cushion Functions Cushion at the heel of the foot Reduces slipping Helps to mechanically pump blood back up the leg from the corium during weight-bearing (see below) Remember to firmly pick out the sulci of the frog when you clean a horse’s foot
67
Shoeing of a horse does what
Shoeing a horse prevents excessive expansion of the hoof when the animal carries weight Also improves traction and creates a barrier between the ground and hoof – protects from injuries Usually combined with trimming
68
What happens to the horse hoof as they walk to allow blood flow
Frog and digital cushion are flattened and widened during weight-bearing This puts pressure on the walls and bars and collateral cartilages causing the walls to spread at the heels Pressure forces blood out of the vascular bed of the foot Since the blood is forced out against some resistance, this provides additional absorption of concussion
69
Cartilages of the equine hoof do what
Lateral or collateral cartilages are a pair of cartilage structures attached to the angles of P3 and extending into the area of the heel proximal to the coronary band of the hoof
70
Bones of the equine hoof
Distal part of the middle phalanx, distal sesamoid bone – “navicular”, and the distal phalanx – “coffin bone” The distal (3rd) phalanx has layers of sensitive laminar corium which interdigitate with the laminae of the hoof
71
Laminitis in equine is
Inflammation of the laminae attaching hoof wall to corium Laminae swells Swelling is trapped inside the wall of the hoof Inhibits blood flow to corium due to compression Corium may degenerate Attachment between wall and corium is lost Pedal bone can rotate or sink within the hoof Puts pressure on sole, may perforate sole
72
Laminitis is caused by
Overload Inflammatory Metabolic diseases
73
Overload in laminitis
reduced weight bearing on a limb (trauma or surgery) causes excessive weight bearing in other limbs
74
Inflammatory in laminitis
A major cause is dietary Sudden increase in the amount of grain (intentionally or accidentally) or rapidly growing fresh spring grass ingested. Grain is full of starch and some will reach the large intestine. Grass is full of fructose polymers which cannot be digested in SI and pass intact to LI As a result there is bacterial overgrowth and fermentation in the large intestine. Toxins are produced. These are absorbed and produce inflammation of the hoof wall
75
Equine metabolic syndrome effect on laminitis
Insulin dysregulation, abnormal fat deposition, difficulty losing weight. “Cresty” neck horses and ponies
76
PPID effect on laminitis
Pituitary pars intermedia dysfunction (PPID) Equine Cushings Cortisol excess causes delayed shedding (results in longhair coats), PU/PD, insulin dysregulation
77
Treatment for laminitis
Treatment – pain relief and anti-inflammatory meds Ice – prevents breakdown of laminae Some changes can be corrected or improved with corrective shoeing and trimming, feed, and management (takes months) Euthanasia if rotation has occurred
78
Effects of laminitis
Laminitis is extremely painful Usually front feet are affected (can be all 4) Horses stand with front feet out and hind limbs under body If all 4 feet affected, all feet are tucked together Horse may lay down a lot and be unwilling to stand Hooves feel warm with increased digital pulses Sole may sink (flatten) P3 may poke through sole Hoof wall develops ridges and curls up at toe
79
Prevention of laminitis
Limit high CHO feeds Especially ponies in Spring Often occurs after sudden introduction to lush pasture grazing or high CHO foods like grain, molasses, and corn Severe illness (retained placenta with metritis) can also be complicated by laminitis Monitor feet carefully and treat at first signs
80
Sand cracks are and are caused by
Vertical cracks in hoof Named for region of occurrence - toe, heel, quarter cracks Cause If begin at solar border result of improper or no trimming If begin at coronary band results from defect in hoof formation Excessive drying of hoof predisposes to the condition
81
Thrush in horses
Degenerative condition of the frog Associated with filth and various micro-organisms. Characterized by black, necrotic, foul smelling material in the affected area
82
Contracted foot/heels in equine
Foot is narrower than normal May be caused by lack of frog pressure and often occurs in horses improperly shod Front more commonly affected than back and can be severe enough to cause lameness known as hoofbound Contracted heels the heels of affected horses are drawn in, the bars are almost parallel and the frog is much reduced in size. Also called contracted hoof or contracted foot.
83
Navicular disease
Chronic degenerative condition of navicular bone Seen in older horses Primarily a disease of the forefeet Trauma of high impact weight bearing (racing) and defective shoeing are contributory factors Often begins with loss of cartilage and inflammation of the bursa between the navicular bone and the deep digital flexor tendon Navicular disease is a common cause of “heel pain” lameness in horses
84
Bovine foot rot
Proliferative inflammation of interdigital space, coronary region and P3. Several micro-organisms cause foot rot Signs: Foul smell, redness, swelling, redness, discharge from damaged interdigital skin Very responsive to antibiotics
85
Interdigital Dermatitis (Slurry Heal)
Infection of the heel bulb and interdigital skin Rarely lame Treated with topical disinfectants such as coppertox. Wear gloves!
86
Interdigital Fibroma
Proliferation of tissue of interdigital cleft Often associated with foot rot and interdigital dermatitis Mass of connective tissue projecting down and between claws Walking becomes painful as corn increases in size
87
Vertical fissures in bovine
usually animal is suffering from overgrown hooves resulting in abnormal weight bearing, may also be laminitic Incidence increases during dry weather which causes hoof wall to become hard and lose its elasticity
88
Horizontal fissures (thimbling) in bovines is
usually occur in mature dairy cattle following attack of laminitis Usually all 8 claws are affected
89
Laminitis in bovine is
Most foot lameness of cattle is directly or indirectly related to laminitis Major cause - ingestion of excessive amounts of grain. Only mildly painful in cattle. The integrity of the lamina and hoof wall and sole are all compromised when laminitis occurs Overgrown and malformed hooves result, haemorrhage in the sole, possibly necrotic toe lesions
90
Horn is and composed of
Boney outgrowth with epidermal covering Similar to hoof - keratin tubules bound to periosteum of underlying bony core by a corium Starts as an epithelial horn bud. Grows out as a solid structure that becomes hollowed out by about 6 months of age Adult animals have hollow horn that communicates with the frontal sinus Male and female animals may have horns Pronghorn antelope are only species to shed horn annually – rest are permanent and grow continuously through life Polled = no horns in a species that was historically horned, though can have remnants
91
Antler is and process of shedding
Tend to be only in males Shed annually Bony growth that is nourished by the velvet on the outside Once grown, a connective tissue ring forms like a tourniquet around the base of the antler to cause velvet slough Antler hardens Late fall/winter the bony base connecting antler to skull weakens and antler falls off
92
Antler harvest methods used to get animal to cooperate
PAINFUL!!! Many methods used to get animals to cooperate Local anesthetic blocks Tourniquet Restraint (physical, chemical)