Intergrative Sensory System SEM2 Flashcards

1
Q

What are the different sensory systems

A

External environment - vision, hearing, taste, smell
Position and movement - balance
Interoceptors - visceral mechanical, thermal + chemical detection

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2
Q

What are characteristics of bipolar sensory neurones

A

Cell body in dorsal root ganglia
Peripheral terminals in dermis/epidermis
Central terminals in dorsal horn of spinal cord

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3
Q

What is the types of mechanosensors for touch, vibration, stretch and pressure

A

Specialised sensory endings - myelinated A β axons for fast conduction of sensory signals

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4
Q

What is the type of mechanosensor for pinches, high pressure and trauma

A

Bare nerve endings - thinly myelinated for faster transmission of pain

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5
Q

What do pacinian corpuscles detect

A

Detect vibrations and deep pressure

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6
Q

What is the role of thermal sensors in skin

A

Distinct sensors for different temperature ranges
Innocuous and noxious ranges covered

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7
Q

How do touch pathways ascend

A

Ascend in ipsilateral dorsal column

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8
Q

Where are touch pathways relayed at

A

Relayed at cuneate/gracile nuclei in medulla

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9
Q

Where do touch pathways cross over into

A

Cross over into the medial lemniscus

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10
Q

Where are touch pathways relayed in following being crossed over into the medial lemniscus

A

Relayed into thalamus and projected to SI cortex

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11
Q

Where do pain pathways cross over into

A

Cross over in the spinal cord

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12
Q

Where do pain pathways ascend in

A

Ascend in contralateral ventrolateral column (spinothalamic tract)

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13
Q

Where are pain pathways relayed in

A

Relayed in thalamus and projected to SI cortex

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14
Q

What does stretching of a muscle spindle drive

A

Drives excitatory input to same muscle to contract and inhibits input to opposing muscle

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15
Q

What is the visual pathway

A

Projection via lateral geniculate nuclei to visual cortex (occipital lobe)

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16
Q

What are V1 cells in visual information processing

A

V1 cells are retinotopic and binocular and important to initial stages of visual processing

17
Q

What causes the movement of the basilar membrane

A

Inside the cochlea sound waves causes the fluid to move which vibrates the basilar membrane and can respond to different frequencies

18
Q

What is the auditory pathway

A

Largely crossover in the lower brain stem
Projects to inferior colliculus then medial geniculate nucleus and to auditory cortex A1 (temporal lobe)

19
Q

What does fluid movement in auditory/sensory transduction cause

A

Fluid movement induced stretch of link fibres opens K+ channels causing depolarisation

20
Q

What does the vestibulo-oculomotor reflex do

A

Maintains direction of gaze during head rotation

21
Q

What does the righting reflex do

A

Maintains balance during tilt-induced activity in muscles

22
Q

What is touch processed through

A

The dorsal column tract

23
Q

What is pain processed through

A

Ventral spinothalamic tract

24
Q

What does lesions at the forebrain level cause

A

Contralateral paralysis in the limbs

25
What does lesions at the spinal cord level cause
Ipsilateral paralysis in the limbs
26
What are the three regions of the motor cortex
Primary motor Premotor Supplementary motor area (SMA)
27
What does the motor cortex evoke
Evokes muscle contraction directly through the control of lower motor neurones and alters strength of spinal reflexes
28
What is the premotor area involved in
Involved in postural preparation for movement
29
What is the supplementary motor area (SMA) involved in
Involved in planning co-ordinated movements
30
What are properties of the corticospinal tract
Controls voluntary movement Projects through internal capsule in midbrain Controls contralateral lower motor neurons in ventral spinal cord
31
What are the effects of a stroke
Occurs near the internal capsule lesioning one or both corticospinal tracts Causes impairment of voluntary movement with increased muscle tone - spasticity
32
What does the pyramidal pathway control
Controls fine/purposeful movement
33
What tract is used for the pyramidal pathway
Corticospinal tract from motor cortex which descends through the brainstem into the spinal cord
34
What is the purpose of the extrapyramidal pathway
Achieves refelx adjustments of posture/balance Modulates muscle tone Delivers coordinated movement
35
What is the pathway of the extrapyramidal pathway
Indirect pathway relaying in the brain stem and regulated by feedback loops from basal ganglia and cerebellum
36
How is the basal ganglia involved in a feedback loop
Forms feedback loop to cerebral cortex to adjust motor output
37
What is the core region of basal ganglia controlled by
The striatum (core region) is controlled by dopamine (DA) contraning neurons that project from substantia nigra