Interpreting liver function tests Flashcards
1
Q
Which of conjugated and unconjugated bilirubin is lipid and water soluble?
A
Conjugated- Water soluble
Unconjugated- Lipid soluble
2
Q
Which enzymes would you expect to see elevated in hepatic issues as opposed to biliary issues?
A
Hepatic- AST and ALT
Biliary- GGT and ALP
3
Q
Which of AST and ALT is the better indicator of acute disease?
A
AST
4
Q
What do the following AST:ALT ratios indicate?
1: 2.5
1: 1.5
1: 1
A
Alcoholic hepatitis
Ischaemic hepatitis
Paracetamol
5
Q
What protein is measured to make a diagnosis of Wilson’s disease and does it increase or decrease?
A
Caeruloplasmin decreases in Wilson’s disease
6
Q
What is AFP used to diagnose?
A
Liver cancer
