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Flashcards in intro Deck (18)
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1
Q

what are the functions of the astrocyte

A

Found in bbb and is key in preventing pathogens from getting in

2
Q

what is the function of microglia

A

able to supply surrounding cells with different neurotransmitters and release ATP for sourounding neuronal use

3
Q

What 2 support cells have NMDA receptors

A

Astrocytes and microglia

4
Q

What is the function of ann oligodendroglia and Schwann cells

A

oligodendroglia-mylein producing cells in the CNS

Schwann cells- mylein producing cells in PNS

5
Q

What is saltatory conduction

A

conductance jumping bw nodes of ranvier to speed up conductance

6
Q

What is MS

A

immune mediated destruction of mylein

7
Q

What are one of the 1st s+s of MS +best way to diagnose

A

some degree of visual disturbance

MRI is gold standard

8
Q

Hwo much energy does the na/k pump use daily

A

50% of ur total energy

9
Q

if you allowed k or na do what it wanted what would be the eq of the cell

A

K- would likely leak out causing the cell to be more neg (-90)

na- would come in causing cell to be more positive (+50)

10
Q

Conc of k, na and cl

A

K higher intracellularaly

na and cl higher extracellularly

11
Q

Temporal vs spacial summation

A

temp- similarly timed signals will meet at hilock and add together to give a bigger signal

Spacial- signals close in space makes it more likely that these will act together

12
Q

what is the threshold of most cells

A

-55mv

13
Q

Where are most voltage gated sod channels

A

axon hillock

14
Q

steps of depolarization

A

sod channels open causing shoot up to +30, then closes and repolarization happens.
voltage gated pot channels open and it leaves ccell (causing hyperpolarization)

15
Q

What is hypocalcemia and hypercalcemia and what does it cause

A

hypo- less ca on outside of cell (causing inside to feel more positive; more excitable (can lead to cramping)

Hypercalcemia- more positive on outside (causing inside to feel more negative; less excitable

16
Q

what happens in extreme increases in extracellular pot

A

cells will not be able to repolarize cuz there is way too much k outside cell so pot from inside wont leave at top of curve

17
Q

what does tetrodotoxin do

A

Blocks volatage gated sodium channels

18
Q

How does docking of vesicles occur

A

calcium activates docking

  • synaptobrevin on neurotrasmitter vessicle attaches to sytaxin and SNAP 25 on membrane
  • vesicle fuses and releases NT