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Flashcards in Intro Lectures Deck (26)
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1

What is pharmacology

The study of interactions of drugs with living systems

2

What is clinical pharmacology

The application of pharmacology principles to patients

3

What is pharmacy

The science of the preparation of drugs

4

What is toxicology

The study of poisons and their treatments

5

Comparative pharmacology

Study of drugs in different species

6

Veterinary clinical pharmacology

Clinical pharmacology applied to veterinary animal species

7

Evidence based medicine

Pharmacological principles based on valid, relevant research and clinical data

8

What is a Drug

Any substance which can affect a biological system.

9

What is pharmacokinetics

ADME
"What the animal does to the drug"
The movement of the drug in the body

10

What is pharmacodynamics

What the drug does to the animal

11

What are the therapeutic principles?

What is being treated
Does the issue need to be treated with a drug
How will the efficacy be monitored

12

What are the sources of drugs

Natural
(Mineral, virus, fungi, bacteria, plant, animal)
Semisynthetic
Synthetic

13

What are virus's used for in pharmacology

Virus or viral particles for vaccines
Fly
West Nile
Distemper
Bovine respiratory syncytial virus

14

Why are fungis used in pharmacology.

Side note- why did the fungi leave the cool party?

BECAUSE THERE WASNT MUSHROOM! Ahhh hahahaha

But really
Antibiotics (pen G from p. Chrysogenum) (cephalosporin C from A chrysogenum)
Antifungals
(Griseofulvin from penicillium griseofulvum)

15

What is bacterias role in pharmacology

Antibiotics
Bacitracin from bacillus subtilis
Polymixin from b. Polymyxa
Streptomycin from s. Gruseus
Gentamicin from micromonospora purpurea

Toxins (for toxoid production)
Tetanus toxin from clostridium tetani

16

What do plants provide for pharmacology

Active ingredients such as:
Alkaloids
Glycosides
Gums
Tannins (2 ns= non nitrogenous)
Fixed oils
Volatile (ethereal) oils (evaporate)
Resins

17

What are alkaloids

Compounds containing basic nitrogen atoms, insoluble in water, but the salts are soluble. Bitter taste, can be precipitated by acids. All of the "ine " suffixes

Atropine
Scopolamine
Morphine
Yohimbine

18

What are glycosides

Sugars combined with other organic structures. (Aglycone or genin)

Digoxin
Digitoxin
Ouabain

19

What are gums

Polysaccharides excreted by certain trees.
Acacia gum from acacia sp.
Tragacanth from astralagus sp.

20

What are tannins. No this isn't slang for what you do at the beach!

(Non nitrogenous- tested over in vet prep).

Poly phenols that produce astringent effect (precipitate proteins).
-the component that dries the mouth in red wines

21

What are fixed oils

Oils that will NOT evaporate when exposed to air!
Cotton seed oil
Castor oil
Linseed oil

22

What are volatile (ethereal) oils

Oils that WILL evaporate when exposed to air.
Resins are formed by polymerization of volatile oils.

Peppermint oil
Turpentine oil
Oil of Clove

23

How are resins formed

Polymerization of volatile oils

24

What animal products are used in pharmacology

Blood
Plasma
Hormones
Toxins
Other

25

What are semisynthetic drugs

Drugs from natural sources but undergo chemical treatment.

Amoxicillin
Ampicillin
Apomorphine

26

What are synthetic drugs

Compounds completely manufactured in the lab - breaking bad meth its in the ppt.

Sulfonamides
Fentanyl
Furosemide
Acepromazine