Intro To Genetics Flashcards
Alleles
Different versions of a gene (e.g., Tall (T) vs. Dwarf (t)).
The genetic makeup (e.g., TT, Tt, t
Genotype
The physical appearance (e.g., Tall, Dwarf).
Phenotype
Identical alleles (TT, rr).
Homozygous (purebred)
Heterozygous (hybrid)
Different alleles (Tt, Rr).
Expressed in the phenotype (Tt or TT = tall)
Dominant
Recessive
Only expressed when both alleles are recessive (tt = dwarf).
DNA consists of two strands forming a twisted ladder.
Double Helix Model
Nucleotide Components
Sugar-phosphate backbone.
Nitrogenous bases:
Adenine (A) pairs with Thymine (T).
Cytosine (C) pairs with Guanine (G).
Humans have _____ chromosomes
22 pairs of autosomes (non-sex chromosomes).
1 pair of sex chromosomes (XX = female, XY = male).
Extra/missing chromosomes (e.g., Trisomy 21 causes Down syndrome).
Aneuploidy
Loss or gain of chromosome segments.
Deletion/Duplication
Law of Segregation
Each parent passes one allele per gene to offspring.
Gregor Mendel Law
Laws of Inheritance
a law that has Different traits are inherited independently (e.g., height doesn’t affect eye color).
Law of Independent Assortment:
a law that has Dominant traits mask recessive ones.
Law of Dominance:
DNA → mRNA (messenger RNA)
Transcription
mRNA → Protein (via ribosomes and tRNA).
Translation
Epigenetics
Environmental factors like diet, stress, and toxins can modify gene activity without changing DNA sequences.
Random changes in DNA that can be beneficial, neutral, or harmful.
Mutation
Mixing of genetic material during sexual reproduction increases variation.
Genetic Recombination
Evolutionary Adaptation
Over generations, populations evolve traits suited to their environment.
Example: People living in high-altitude areas develop adaptations for oxygen efficiency.
Genetic Testing
Identifies inherited diseases (e.g., BRCA gene for breast cancer).
Replacing faulty genes to treat genetic disorders (e.g., cystic fibrosis).
Gene Therapy