Intro to Pharmacology Quiz Flashcards
Match the statement: Adverse effects
A frequency based listing of potential side effects
Match the statement: contraindications and warnings
identifies patients at risk for serious adverse effects
Match the statement: Pharmacokinetic property
Elimination half-life
Match the statement: Pharmacodynamic property
Reduces blood pressure
What is the difference between pharmacokinetic and pharmacodynamic properties?
Pharmacokinetic has to do with characteristics of the DRUG, whereas pharmacodynamic has to do with what effects the drug has on the BODY
Identify the most correct statement:
a) Pharmacologic effects can be related to an excessive dose.
b) Patients should consult an attorney as soon as they notice a side effect.
c) Medication allergies are always considered pharmacologic adverse effects.
d) Adverse effects are rarely seen once the FDA approves a medication.
a
Select the most accurate statement about the drug approval process.
a) Drugs are tested in increasingly larger study populations prior to approval until every rare side effect is identified.
b) The focus of clinical trials is on the elderly, and on patients known to have multiple medical problems.
c) The Food, Drug, and Cosmetic Act was implemented following reports of serious adverse events related to delays in the approval of new products.
d) Once a drug is approved and use is widespread the frequency of reports of adverse effects usually increases.
d
Match the correct statements: A highly water soluble drug…
is eliminated by the kidney and has a small volume of distribution
has a large volume of distribution, may require complex metabolism prior to elimination, can be responsible for metabolic drug
eliminated by the kidney and has a small volume of distribution.
Match the correct statement: A poorly water soluble drug…
is eliminated by the kidney and has a small volume of distribution
has a large volume of distribution, may require complex metabolism prior to elimination, can be responsible for metabolic drug
has a large volume of distribution, may require complex metabolism prior to elimination, can be responsible for metabolic drug
Match the correct statement: A drug classified as an antagonist…
has receptor affinity without efficacy
has receptor affinity and efficacy
has receptor affinity without efficacy
Match the correct statement: A drug classified as an agonist…
has receptor affinity without efficacy
has receptor affinity and efficacy
has receptor affinity and efficacy
Match the correct response:
The volume of distribution…
Describes the ability of a medication to cross cell membranes (increases as water solubility decreases)
If drug B has a higher plateau response than drug A, then is drug B is more or less efficacious?
More efficacious
_______ medications take a long time to reach a peak effect after multiple doses, and are also more difficult to titrate to patient response.
Long half-life
How are the therapeutic window and index of hydrophilic meds impacted in acute renal failure?
They narrow with water soluble meds
