Jeopardy Review 7/28 Flashcards
Which organism is responsible for GAS?
Strep pyogenes
What is a gram positive cocci in pairs?
Strep pneumoniae
What is a gram +, coagulase - cocci in clusters?
Staph epidermidis (or any Staph that is not Staph aureus)
What species of streptococci is often found in the gut?
Enterococci
Which gram negative diplococcus is frequently found in the middle ear?
M. catarrhalis (NOT H. influenzae, which is a gram neg. COCCOBACILLUS)
Which class of antibiotics inhibits transpeptidase (which inhibits cell wall synthesis)?
Beta lactams
Which class of antibiotics inhibit protein synthesis, generate defective proteins, and treat serious gram negative infections?
Aminoglycosides (tobra/gentamycin)
Which abx class inhibits two consecutive steps in bacterial folic acid synthesis?
Co-trimoxazole (aka Bactrim)
What antibiotic is active against gram + bacteria, including MRSA, and is NOT orally absorbed?
Vancomycin
What are 3 abx that are useful against anaerobes?
Carbapenems, metronidazole, ampicillin sulbactam, clindamycin
What is an example of a 1st generation cephalopsorin?
Cefazolin or cefalexin
What is a 3rd generation cephalopsorin that has mid level gram + coverage, usually dosed once a day, and is given only through injection?
Ceftriaxone
You have 2 abx: one gram + and one gram -, that are both OK to use in patients with serious PCN allergies. What are they?
Aztreonam, vancomycin
What antibiotic is used for vancomycin resistant staph?
Linezolid
What class of broad spectrum abx are active against serious gram - organisms, and are effective when given orally by inhibiting DNA gyrase activity (similar to topoisomerase inhibition)?
Fluoroquinolones
