Introduction Flashcards

(41 cards)

1
Q

defined molecular biology as the study of dna

A

james watson

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2
Q

head of the natural science division of the rockfeller foundation

A

warren weaver

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3
Q

first to use the term molecular biology

A

warren weaver

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4
Q

deals with molecular techniques for handling and analysis of nucleic acids

A

diagnostic molecular biology

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5
Q

discovered dna and extracted nuclein

A

john friedrich miescher

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6
Q

first to demonstrate bacterial transformation

A

frederick griffith

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7
Q

type s

A

virulent

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8
Q

type r

A

non virulent

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9
Q

implicated that DNA is responsible for bacterial transformation

A

avery, macleod, mccarty

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10
Q

enzyme that digest proteins

A

proteases

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11
Q

enzymes that breaks apart RNA

A

ribonucleases

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12
Q

enzymes that act on DNA

A

DNases

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13
Q

took the photo 51

A

rosalind franklin & raymond gosling

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14
Q

studies of DNA’s structure through X-ray diffraction

A

(X-ray crystallography)

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15
Q

helped confirmed that DNA is the genetic material by performing experiments

A

alfred hershey and martha chase

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16
Q

performed chromatographic methods about adenine, thymine, guanine, cytosine

A

erwin chargaff

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17
Q

adenine is equal to

18
Q

guanine is equal to

19
Q

published in nature, the first correct model of the DNA molecule

A

james watson and francis crick

20
Q

utilized franklin’s “photo 51”

A

james watson and francis crick

21
Q

they performed the first known successful DNA recombinant experiment

A

herbert boyer and stanley norman cohen

22
Q

seperately developed techniques for rapid DNA sequencing

A

walter gilbert and frederick sanger

23
Q

invented the pcr technique

24
Q

presented the zinc finger nucleases

A

nikola panayot pavletich and carl pabo

25
first to generate the mammalian clone, dolly the sheep
sir ian wilmut
26
a roundworm who became the first multicellular organism to have its entire genome decoded
caenorhabditis elegans
27
first crop to have its entire genum decoded
rice
28
this project completely mapped and identified all of the genes of the human genome
human genome project
29
enzymes that can be engineered to cut specific dna sequences
talens
30
meaning of talens
transcription activator-like effector nucleases
31
utilized for genome editing purposes
crispr-cas9
32
meaning of crispr
clustered regularly interspaced short palindromic repeats
33
refers to the analysis of nucleic acids and proteins for diagnosis
molecular pathology
34
PREDICT disease progression
prognosis
35
DETECT normal and disease states
diagnosis
36
identifying the gene expression pattern
redefinition of diseases
37
molecular biology enabled clinicians to identify genes that have the potential of causing cancer
detection of cancer
38
molecular techniques have enabled the detection of pathogens
detection of infectious diseases
39
genetic screeing for the presence of proteins involved in drug metabolism
treatment of diseases
40
studies how drug responses occur concerning an individual's genome
pharmacogenomics and personalized medicine
41
diagnostic molecular techniques have been of great assistance for predicting the manifestation of genetic diseases
diagnostic of genetic diseases