Introduction Flashcards

1
Q

What are the layers of th skin?

A

Sub cutis
Dermis
Epidermis

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2
Q

What is the sub cutis?

A

Innermost layer of kin

Fat energy store that offers insulin and fibrous bands that anchor skin to fascia

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3
Q

What is the dermis?

A

Collagen and elastic matrix

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4
Q

What is in the dermis?

A

Mucopolysaccharise gel, fibroblasts, dermal dendrites cells and macrophages

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5
Q

What are the types of cell in the epidermis?

A

Keratinocytes
Langerhans
Melanocytes

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6
Q

What cells form the majority of th epidermis?

A

Keratinocytes

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7
Q

What is the function of langerhans cells in the epidermis?

A

Process antigens and migrate to lymph nodes to induce immune response

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8
Q

What are melanocytes?

A

Cells that are excreted and phagocytksed into keratinocytes

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9
Q

What are the layers of the epidermis?

A
Stratum corneum
Stratum lucidum
Stratum granulosum
Stratum spinosum
Stratum basale
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10
Q

What is the structure of the stratum corneum?

A

Dead cells in a hard protein envelope- cells contain keratin and are surrounded by lipids

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11
Q

What is the structure of the stratum lucidum?

A

Dead cells that lie within keratohyalin

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12
Q

What is the structure of he stratum granulosum?

A

Keratohyalin and a hard protein envelope form

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13
Q

What happens in the stratum granulosum?

A

Lamellar bodies release lipids and cells die

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14
Q

What is the structure of th stratum spinosum?

A

Keratin fibres and lamellar bodies

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15
Q

What happens on the stratum basale?

A

Cells divide by mitosis and some newly formed cells become the cells of the more superficial strata

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16
Q

What are the regions of the nail?

A

Lunula
Nail plate
Hyponychium

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17
Q

What are the 3 stages of hair growth?

A

Anagen
Catagen
Telogen

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18
Q

What is the anagen phase?

A

Active phase pf hair growth

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19
Q

What is the catagen phase?

A

Growth stops and follicle shrinks- 2-3 week phase

20
Q

What is the telegenic phase?

A

Resting phase for 1-4 months, up to 10% hair on normal scalp

21
Q

What are the functions of the skin?

A
Thermoregulation
Immune
Barrier
Sensation
Vit D synthesis
Interpersonal communication
22
Q

What are the thermoregulative functions f the skin?

A

Insulation

Heat transfer

23
Q

What does the skin protect against?

A

MEchanical
Chemical
UV light
Microorganisms

24
Q

What does the skin keep in?

A

Water
Electrolytes
Macromolecules

25
What sensations is skin involved in?
Temperature Touch Pain
26
What is UV light used for?
Convert 7-dehydrocholesterol to cholecalciferol
27
What can skin disease cause?
``` Disfirgurement Discomfort Disability Depression Death ```
28
What are the types of causes of skin disease?
External | Internal
29
What are the eternal causes of skin disease?
``` Temperature UV light Chemical Infection Trauma ```
30
What are the chemical causes of skin disease?
Allergen or irritant
31
What are the internal causes of skin disease?
Systemic disease Genetics Drugs Infection
32
What is a macule?
Small circumscribed area
33
What s a patch?
Large circumscribed area
34
What is a papule?
Small raised area
35
What is a plaque?
Larger raised area
36
What isa vesicle?
Small, fluid filled
37
What is a bulla?
Large, fluid filled
38
What is a pustule?
Small pus filled
39
What is an abscess?
Large pus filled
40
What is an erosion?
Loss f epidermis
41
What is an ulcer?
Loss of epidermis and dermis
42
What is classed as "small"?
<5mm
43
What investigations should be done for a bacterial infection?
Charcoal swab- ask for microscopy, culture and sensitivities
44
What investigations should be done or a viral infection?
Viral swab for PCR- skin or vesicle/bulla | Is systemic illness, take throat swab
45
What is taken for a fungal infection?
Skin scraping Nail clipping Hair sample
46
What is the common way to take a skin biopsy?
Punch biopsy
47
When is a skin biopsy done?
When there is no sign of infection or unknown cause of reaction