Flashcards in Introduction to immuno sero Deck (66)
Area of biology that concerned with the process by which all living organism defense themselves against infection.
Study of any protection from any invading substances.
Resistance to infectious agents
Study of antigens and antibody in vitro.
Study of blood serum
Between hapten and ag with IG
Development of allergies and theories of complement
Damage by immune system
Blood banking or blood groups
Main infection: is self/non self discrimination
Ability of an organism to recognize and defend itself against specific pathogen or antigens; resistance to infectious agents
Immunity an organism is born with
It function in the early stages of host defenses in response to any foreign substances referred to as antigen
Examples of autoimmune disease:
Systemic lupos erythematosus
Skin, Mucus, saliva, tears
Can give growth to some bacteria
Fatty acids in sweat
Can breakdown cell wall bacteria and destabilize bacterial membranes
Lysozymes and phospholipase
Prevent growth of bacteria
Low pH sweat and gastric secretions
Has an antimicrobial property
Acts as opsonins; helps promote phagocytosis
Characterized by edema and phagocytic cells. Found in serum and site of infection
Humoral barriers to infection
Once activate can lead to increased vascular permeability, recruitment of phagocytic cells, lysis and opsonization of bacteria
Contribute to the non-specific defenses because of their ability to increase vascular permeability and act as chemotactic agents for phagocytic cells.
By binding iron; these protein limit bacterial growth.
Lactoferrin and transferrin
Limit virus replication cells
Breaks down the cell of bacteria
Cytokines that participate in the regulation of immune responses, inflammatory reactions and hematopoiesis
Interleukin 1 or IL-1
T-lymphocyte regulate the growth and differentiation of certain lymphopoietic and haemopoietic cells.
Interleukin -2 and -3 or IL2 and 3
Regulates eosinophil growth and activation and thus plays an important role in disease associated with increased levels of eosinophils, including asthma.
Essential role in the final differentiation of B cells into IG secreting cells, inducing myeloma/plasmacytoma growth, nerve cell differentiation and in hepatocytes, acute-phase reactant, activates resident lymphocytes and vascular endothelia.
Interleukin -6 or BSF-2 or interferon beta 2 or B cells stimulating factor -2