Iodine Compounds Flashcards

(60 cards)

1
Q

Most commonly used contrast agent

A

Water-soluble iodine compounds

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2
Q

Water-soluble iodine compounds aka

A

Aqueous Iodine Compounds

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3
Q

5 ways to administer water-soluble iodine compounds

A
Orally
Intrathecally
Intravenously 
Intraarterially
Directly injected into structure
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4
Q

4 departments that use water-soluble iodine compounds

A

Cath lab
EP
OR
Radiology

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5
Q

Isovue M is given

A

Intrathecally

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6
Q

Isovue is given

A

IV
Intraarterially
Direct injection

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7
Q

water-soluble iodine compounds are… Based; and contain

A

Carbon

Iodine atoms and various other atoms

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8
Q

water-soluble iodine compounds molecules vary ……. And some contain more….. Than others

A

In size

More iodine

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9
Q

What property of iodine makes it a good positive contrast agent

A

High atomic number

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10
Q

Name studies that use water-soluble iodine compounds

A
Urinary studies - IVU, cystogram
Biliary studies- Cholangiography 
Arthrography
Cardiovascular interventional exams
CT scan
Other fluoroscopic studies
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11
Q

Brand names of water-soluble iodine compounds

A
Optiray
Visipaque
Cystographin
Isovue M
Hypaque
Cystografin
Gastrografin
Isovue
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12
Q

Oily Iodine Compounds aka

A

Ethiodized oils

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13
Q

When is oily iodine compounds used

A

When absorption is not desired

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14
Q

3 studies that may used oily iodine compounds

A

Hysterosalpingograms
Bronchography
Myelography

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15
Q

What has replaced oily iodine compounds

A

Newer aqueous iodine agents

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16
Q

Brand names of water-soluble iodine compounds

A
Optiray
Visipaque
Cystographin
Isovue M
Hypaque
Cystografin
Gastrografin
Isovue
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17
Q

Oily Iodine Compounds aka

A

Ethiodized oils

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18
Q

When is oily iodine compounds used

A

When absorption is not desired

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19
Q

3 studies that may used oily iodine compounds

A

Hysterosalpingograms
Bronchography
Myelography

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20
Q

What has replaced oily iodine compounds

A

Newer aqueous iodine agents

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21
Q

Ionic means

A

of, relating to, or using ions.

(of a chemical bond) formed by the electrostatic attraction of oppositely charged ions.

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22
Q

Ionic contrast is ——- contrast media

A

Tri-iodinated

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23
Q

Ionic contrast contain– and —-

A

Sodium and Meglumine salts (cation)

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24
Q

What happens once the ionic contrast is injected

A

It dissociates into ions called anion and cations

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25
Ionic contrast contains how many iodine atoms
3
26
Anions
Negatively charged particles
27
Cations
Positively charged particles
28
What are ionic contrasts known to do
Bond to something such as blood
29
When were non-ionic contrasts introduced
1980s
30
Why are non-ionic used with pt with higher risk for reactions
Because is doesn't dissociate
31
Most departments use-- exclusively
Water-soluble Iodine Non-ionic Contrast
32
Water-soluble iodine compounds | 3 features of ionic that is different than non-ionic
1. Dissociates into separate ions when injected 2. Creates hypertonic condition 3. Increases blood osmolarity
33
Water-soluble iodine compounds | 3 features of non-ionic that is different than ionic
Does not dissociate when injected Remains isotonic No significant increase in blood osmolarity
34
Hypertonic solution
is one where the concentration of solutes is greater outside the cell than inside it.
35
Isotonic
one in which the concentration of solutes is the same both inside and outside of the cell. Does not change blood composition
36
Osmolality
Concentration of particles in a solution
37
What is the Osmolality of blood
300 milliosmol per kg | 300 mOsm/kg
38
Example of ionic monomer
Diatrizoate and sodium salt
39
Osmolality of ionic monomers
Diatrizoate is considered a high-osmolality contrast agent 1530 mOsm/kg
40
Osmolality of non-ionic dimmer Iotrolan and iodixanol
290 mOsm/kg
41
The lower the Osmolality contrast means
Less chance of reaction to contrast
42
Osmolality of isotonic
Solution has the same Osmolality as plasma
43
Osmolality of hypertonic
Greater Osmolality than plasma (ionic contrast)
44
Osmolality of hypotonic
Less Osmolality than plasma
45
Who is at risk for contrast mediA reactions ; 6
1. Hx of allergies esp shellfish, seafood,iodine products 2. Asthma, hay fever 3. Pts with previous adverse reactions 4. Over 60 y/o 5. Cardiac disease 6. African American
46
What lab levels do we check before contrast
BUN GFR Creatinine
47
What is SFMC premedication to prevent reactions
Prednisone 50mg orally every 6 hours; Starting 13 hours before contrast: 1 dose at 13 hours 1 dose at 7 hours 1 dose at 1 hour Total of 150 mg Benedryl (Diphenhydramine). 50 mg orally 1 hours before contrast
48
Vasovagal response
When the contrast media stimulates the vagus nerve causing cardiovascular changes
49
Signs of vasovagal response
Increase in vasodilation of arterioles. Diaphoresis, sinus bradycardia, hypotension May be life threatening but usually not
50
Anaphylaxis or anaphylactic reaction is a
serious allergic reaction that is rapid in onset and may cause death.
51
Symptoms of anaphylaxis
itchy rash, throat or tongue swelling, shortness of breath, vomiting, lightheadedness, and low blood pressure.
52
Mild reactions that don't need tx
Warm feeling Metallic taste in mouth Nausea/ vomiting Coughing/ sneezing
53
Moderate reactions
Urticaria hives Erythema Bronchospasm Facial swelling Antihistamine given orally, iv, or injection
54
Severe reactions
``` Laryngeal or bronchial edema Dysphasia / difficultly swallowing Cyanosis Seizure Respiratory arrest Cardiac arrest Death ```
55
What are the step if pt coded
``` Dial 4000, if pt is coding-code blue Get code cart Unplug defibrillator Get O2 Direct traffic ```
56
Treatment for severe reaction
Maintain open airway Check vital signs Call code Epinephrine Solumedrol
57
Most reactions happen within
10-20 minutes Don't leave pt unattended Have tx stuff at hand
58
Contraindications to Water-Soluble iodine compounds
``` Multiple myeloma Sickle cell disease Allergic to iodine Pheochromocytoma Hepatic or renal failure Anuria ```
59
Reasons why you would reject contrast - looking at the bottle
Expired Open or seal is broken Color change/ not clear Chrystal's formed near top due to air getting into bottle Manufacturer recall, check lot number on bottle, discontinue use
60
Contrast administration checklist
``` Select correct contrast for procedure check expiration date Read bottle label Show Doctor the label Draw up or assist in drawing up contrast Re-check label and say name and expiration date out loud to the doctor Save the empty bottle Watch pt for reactions ```