ISBB

Question 1

Chinese variolation

Answer 1

Inhale powder

Question 2

Cook carier of typhoid

Answer 2

Mary mallon

Question 3

Study of antibody structure

Answer 3

Geral edelmam, Rodney porter

Question 4

Antibody diversity developed by

Answer 4

Susumu tonegawa

Question 5

Developmental abnormality of the third and fourth pharyngeal pouches that affects thymic develoment

Answer 5

DiGeorge Anomaly

Question 6

Small solubke proteins that regulate the immune system, orchestrating both innate immunoty and the adaptive response to infection; these chemical messengers, produced by several different types of cells, have activity-modulating effects on the hematopoietic and immune systems through activatiom of cell bound receptor proteins

Answer 6

Cytokines

Question 7

Family of cytokines that enhance motioity and promote migration of many types of WBCs toward the source of the chemokine (chemotaxis)

Answer 7

Chemokine

Question 8

Sedimentation coefficient of IgA, IgG, and IgD

Answer 8

7s

Question 9

Sedimentation coefficient if IgE

Answer 9

8s

Question 10

Sedimentation coefficient of IgM

Answer 10

19s

Question 11

Papain fragmentation result

Answer 11

2Fab + Fc

Question 12

Pepsin fragmentation result

Answer 12

F(ab)2 + Fc’

Question 13

Sirface marker of NK cells

Answer 13

CD 16 & CD56

Question 14

Proinflammatory cytokine

Answer 14

Interleukin 8

Question 15

Most common agents are drugs and insect stings

Answer 15

Anaphylactic reactions

Question 16

Most common congenital immunodeficiency

Answer 16

Selective IgA deficiency

Question 17

Severe recurrent infections, glumerulonephritis

Answer 17

C3 deficiency

Question 18

Lupuslike syndrome, recurrent infection, atherosclerosis

Answer 18

C2 deficiency

Question 19

DAF, CD59 (MIRL) deficiency

Answer 19

PNH

Question 20

HLA-B27 is seen in

Answer 20

Ankylosing spondylitis

Question 21

Mixed lymphocyte reaction is in what test

Answer 21

Cellular assay

Question 22

Most specific antibody for SLE

Answer 22

Anti-dsDNA

Question 23

HRP-2 antigen

Answer 23

P. Falciparum

Question 24

Dil. Household bleach prepared daily inactivates HBV within

Answer 24

10 mins

Question 25

Dil. Household bleach daily inactivates HIV within

Answer 25

2 mins

Question 26

HLA antigen detection using

Answer 26

Microlymphocytotoxic test

Question 27

Fluorescenancintense apple-green color

Answer 27

Fluorescein

Question 28

Fluoresce an orange-red color

Answer 28

Rhodamine

Question 29

EDTA-anticoagulated amples are preferred (pink , purple)

Answer 29

DAT, Direct AHG Test

Question 30

ISBT 001

Answer 30

ABO

Question 31

Greatest to least amount of H antigen

Answer 31

O>A2>B>A2B>A1>A1B

Question 32

Anti- A1 lectin

Answer 32

Dolichos biflorus

Question 33

Anti-H lectin

Answer 33

Ulex europeaus

Question 34

Antigens passively adsorbed onto the RBC membrane from the plasma

Answer 34

Lewis antigen

Question 35

Diminished on the mother’s RBCs during pregnancy

Answer 35

Lewis antigen

Question 36

HLA on red cells

Answer 36

Bg, Bennett - Goodspeed

Question 37

Associated wifh C4

Answer 37

Chido, Rodgers

Question 38

Cold agglutinins in the serum of normal individuals and in patients with acquired hemolytic anemia; Wiener and coworkers, gave a name to one such agglutinin, calling its antigen “I” for individualit. The antibody reacted to most blood specimens tested

Answer 38

Anti-I

Question 39

Found in renal patients dialyzed with formaldehyde sterilized equipment

Answer 39

Anti-N like antibody

Question 40

Produce by S-s-u (-), Blacks

Answer 40

Anti-U

Question 41

Safest blood a recipient can receive is his or her own blood

Answer 41

Autologous transfusion

Question 42

Shelf life of blood stored with COD-A1

Answer 42

35 days

Question 43

Whole blood from which cryoprecipitate and/or platelets have been removed

Answer 43

Modified whole blood

Question 44

Preparation of leukopoor RBCs

Answer 44

Centifugation, filtration, saline-washing

Question 45

Components of cryoprecipitate

Answer 45

Fibrinogen (150 mg) AHF (80 Units) vWF Factor XIII

Question 46

Indication of irradiated blood comonents

Answer 46

Prevention of TA-GVHD, inactivate T cells

Question 47

Facilitate oxygen transfer into the platelet bag and oxygen consumption by platelets

Answer 47

Platelet agitation

Question 48

Synthetic vasopressin analogue that can stimulate release of vWF

Answer 48

DDAVP (desmopressin)

Question 49

Associated with posttransfusion hepatitis of unknown etiology (nonA-G). After the initials of the first patient from who, the girus was isolated (TT)

Answer 49

TTV

Question 50

Due to anti-leukocyte antibodies, leukoreduced blood components should be used

Answer 50

Transfusion-associated acute lung injury (TRALI) or noncardiogenic pulmojary edema (NCPE)

Question 51

Iatrogenic, physician caused At risk are children, elderly patients and patients with normovolemic anemia, cardiac disease,cthalassemia major or sickle cell disease

Answer 51

Circulatory overload

Question 52

Transfusion hemosiderosis Accumulation of iron in heart, liver, and endocrine glands At risk are the transfusion-dependent patients: cingenital hemolytic anemia, aplastic anemia and chronic renal fialure

Answer 52

Iron overload

Question 53

Young RBCs, longet lifespan

Answer 53

Neocytes

Question 54

Major cause of transfusion associated fatalaties

Answer 54

Clerical error

Question 55

Primary advantage of gel technology

Answer 55

Standardization