ischemic heart disease Flashcards

(67 cards)

1
Q

DDx of chest pain: MI

A
atherosclerotic disease
anomalous coronary arteries
HTN urgency
pulmonary HTN
aortic valve disease
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2
Q

DDx of chest pain

A
acute aortic syndrome (dissection, intramural hematoma)
pericarditis
PE
GERD, spasms, achalasia
pulmonary (pneuothorax, pneumonia_
chest wall
anxiety
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3
Q

cardiac markers good, ECG normal but patient still has chest pain

A

aortic dissection
PE
-want to rule those out

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4
Q

chest pain history

A
location
character
radiation
intensity
duration
frequency 
associated symptoms
exacerbating/relieving factors
pattern over time
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5
Q

where is it bad for pain to radiate to?

A

neck or arms

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6
Q

branches off left anterior descending

A

called diagnol

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7
Q

branches off the left circumflex

A

called marginal

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8
Q

non-atherosclerotic coronary artery disease

A

coronary vasospasm
anomalous coronary arteries
coronary arteritis (Kawasaki’s, giant cells)
myocardial bridge
coronary dissection: young (30’s), female
coronary embolization

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9
Q

metabolic syndrome

A
HTN
abdominal obesity
HLD 150
fasting plasma glucose >100
associated with inflammation, coagulation abnormalities, progression to type 2 DM
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10
Q

risk factors for atherosclerotic heart disease

A

smoking
HTN
diabetes

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11
Q

why is it difficult to get BP in optimal range in elderly?

A

stiffer blood vessels

-may get light headed when stand up

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12
Q

novel risk factors for atherosclerotic disease

A
  • chronic inflammation
  • elevated hsCRP
  • homocytsteine
  • chronic kidney disease
  • coagulation abnormalities
  • chronic infection
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13
Q

MI: secondary causes

A
  • severe anemic
  • hypoxemia
  • uncontrolled HTN
  • severe LVH
  • uncontrolled tachycardia
  • thyrotoxicosis
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14
Q

manifestation of coronary artery disease

A
  • chronic stable angina
  • unstable angina: new or changing chest pain
  • MI
  • ischemic cardiomyopathy (CHF)
  • sudden cardiac death
  • silent ischemia
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15
Q

which angina needs to be treated?

A

unstable angina

-dynamic process

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16
Q

angina

A

visceral discomfort

  • feels like pressure
  • diffuse and sub-sternal
  • dyspnea, sweating, nausea, light headness
  • provoked by physical exertion, emotional upset, heavy meal, working in cold temperature
  • rest makes better
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17
Q

where does pain radiate to for aortic dissection?

A

to back

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18
Q

typical angina

A

sub sternal

brought by exertion

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19
Q

angina equivalents

A
  • dyspnea
  • arm, jaw, or back pain
  • nausea
  • sweating
  • fatigue
  • silent ischemia
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20
Q

atypical signs in

A

women, diabetics, eldery

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21
Q

ischemic heart disease evaluation

A

history
physical
ECG

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22
Q

ST elevation means

A

means infarction

-ischemia, cells are dying

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23
Q

coronary insufficiency will give

A

ST depression

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24
Q

upward ST depression

A

benign

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25
flat ST depression
pathological
26
dynamic ECH changes with chest pain at rest
send to heart catheter lab | -DON'T do stress test
27
can see inverted T waves with
long standing HTN LVH previous MI
28
alternatives for ST elevation: non chest pain, stable, in previous heart attack
-aneurysm
29
Q waves instead of R waves
loss of myocardium
30
large p waves means
right atrial enlargement - caused by pulmonary HTN - rotates heart, makes R wave progression diminish
31
who can have large P waves
in COPD
32
UAP versus NSTEMI
UAP-> new, rest or worse pain physical exam often normal ST changes-> 50% have non
33
high risk chest pain
``` recurrent pain positive markers persistant ECH changes unstable hemodynamics arrhythmia (VT) Low EF previous CABG diabetes renal insufficiency ```
34
Q wave and T wave inversion, pattern of
inferior MI | -from an occluded RCA
35
treatment for high risk chest pain
- ASA, heparin, beta blockers, morphine, O2, nitrates - clopidogrel, antithrombin therapy-heparin/Lovenox - glycoprotein IIb, IIIa receptor target-tirofiban, abciximab, eptifibatide
36
when is reperfusion therapy needed?
only in STEMI with <12 hours pain duration
37
management for STEMI
- ST elevation >1 mm in 2 or more leads - monitor, O2, ASA, heparin, beta blockers, nitrates, morphine - pain less than 12 hours-> attempt reperfusion
38
who is at highest risk and needs surgery?
left mains stenosis 3 vessels (reduced LV function) 2 vessel disease (prox LAD) multi-vessel diabetics
39
diagnostic tests are only as accurate (stress test)
the group you apply it to
40
treatment for STEMI in acute coronary syndrome is
take them to the cath lab
41
NSTEMI acute coronary syndrome
inadequate blood flow to a segment of the myocardium caused by transient or high grade occlusion or epicardial coronary artery ECG could be normal elevated cardiac enzyme (troponin)
42
STEMI acute coronary syndrome
complete occlusion ST elevation in 2 or more ECG or new LBBBB cardiac enzymes elevation
43
presenting symptoms of acute coronary syndromes
rapidly accelerating exertional angina | unprovoked angina
44
atypical presentation of acute coronary syndromes
``` women elderly diabetics CHF -dyspnea ```
45
diagnosis of ACS
``` target history, physical exam ECH within 10 min of arrival CXR cardiac markers echo ```
46
initial management of ACS
``` aspirin morphine nitrates blood chemistries, CBC, cardiac markers ECG ```
47
ST elevation
injury
48
ST depression
ischemia
49
inferior leads
RCA
50
septal leads
LAD
51
antieror leads
LAD
52
high lateral leads
diagonal or LCX
53
PCI
best treatment if given in a timely manner
54
adjunctive therapies for ACS
``` aspirin clopidogrel anticoagulants beta bockers nitrates morphine ACE-I or ARB ```
55
NSTEMI ACS initial management
``` anti-platelet (aspirin, clopidogrel, IIB/IIIA inhibitors) anticoagulants (heparin, LMWH) beta blockers nitrates morphine ACE-I lipid lowering therapy ```
56
long term ACS
``` aspirin for life clopidogrel for at least 1 year ACE-I beta-blockers S-L nitro lipid lowering therapy (high dose) smoking cessation tight control diabetics tight control blood pressure ```
57
complications
``` recurrent ischemia or infarction ventricular arrhythmias conduction disturbances pericarditis cardiogenic shock ```
58
right ventricular infarction
``` occluded right marginal from RCA-> damage RV -occurs in inferior STEMI hypotension elevated JVP (kussmaul sign) clear lungs ``` *give fluids*
59
an inferior infarction can often develop?
heart block | -give atropine
60
right ventricular infarction management
give fluids
61
papillary muscle rupture
usually inferior MI sudden hypotension and pulmonary edema MR
62
S4 sound could mean
LVH | -HTN heart disease
63
drug coated stents
less ingrowth | longer blood thinner
64
non drug coated stents
more ingrowth | less duration of taking blood thinner
65
CABG
left internal mammary artery | -LIMA into LAD
66
what vein will never have a balloon?
Left main stenosis | -they go to surgery
67
slight depression of the PR segment
acute pericarditis