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**Rapid Review** > Key associations > Flashcards

Key associations Flashcards

(85 cards)

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1
Q

Ovarian mets from gastric carcinoma or breast cancer

A

Krukenberg tumor (mucin-secreting signet ring cells)

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1
Q

Primary liver cancer

A

HCC (chronic hepatitis, cirrhosis, hemochromatosis, alpha1-antitrypsin def’y)

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2
Q

SIADH

A

Small cell carcinoma of lung

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3
Q

Acute gastric ulcer associated wtih severe burns

A

Curling ulcer (greatly reduced plasma volume results in sloughing of gastric mucosa)

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3
Q

Bacterial meningitis in kids

A

Strep pneumo

Neisseria meningitidis

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4
Q

Site of atherosclerosis

A

Abdominal aorta > Coronary artery > Popliteal artery > Carotid artery

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5
Q

HLA-B27

A

Ankylosing spondylitis, reactive arthritis, ulcerative colitis, psoriatic arthritis

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5
Q

Tumor of adrenal medulla (kids)

A

Neuroblastoma (malignant)

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5
Q

Tumor of adrenal medulla (adults)

A

Pheochromocytoma (usually benign)

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6
Q

Acute gastric ulcer assoc w/CNS injury

A

Cushing ulcer (increased ICP stimulates vagal gastric secretion)

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7
Q

Nephrotic syndrome - kids

A

MCD

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8
Q

Infections in CGD

A

Staph aureus, E Coli, Aspergillus (Catalase +)

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8
Q

t(8;14)

A

Burkitt lymphoma (c-myc activation)

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10
Q

Cardiac manifestation of lupus

A

Libman-Sacks endocarditis (nonbacterial, affects both sides of mitral valve)

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10
Q

Thyroid cancer

A

Papillary carcinoma

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11
Q

Brain tumors - adults

A

Supratentorial: mets>astrocytoma (including GBM)>meningioma>schwannoma

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12
Q

Brain tumors - kids

A

Infratentorial: Medulloblastoma (cerebellum) or supratentorial: Cranopharyngioma

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12
Q

Gynecologic malignancy

A

Endometrial carcinoma (most common in US)

Cervical carcinoma (most common world wide)

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12
Q

Recurrent inflammation/thrombosis of small/medium vessels in extremities

A

Buerger disease

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13
Q

Malignancy - kids

A

ALL, medulloblastoma (cerebellum)

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13
Q

Primary hyperaldosteronism

A

Adenoma of adrenal cortex

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14
Q

Cushing syndrome

A
  • Iatrogenic cushing (from steroid therapy)
  • Adrenocortical adenoma (secretes excess cortisol)
  • ACTH-secreting pituitary adenoma
  • Paraneoplastic Cushing (due to ACTH secretion by tumors)
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15
Q

Glomerulonephritis (adults)

A

Berger disease (IgA nephropathy)

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15
Q

Nephrotic syndrome - Adults

A

FSGS

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16
Lysosomal storage disease
Gaucher disease
17
Congenital heart murmur
MVP
17
Hypopituitarism
Pituitary adenoma (usually benign tumor)
17
Ovarian tumor (benign, bilateral)
Serous cystadenoma
19
Congenital conjugated hyperbilirubinemia
Dubin-Johnson syndrome
20
Mets to bone
Prostate, breast\> Lung \> Thyroid
22
Food poisoning - exotoxin
S. aureus, B. cereus
23
Type of non-Hodgkin
Diffuse large cell
24
Pulmonary HTN
COPD
25
Bleeding disorder with Gp1b deficiency
Bernard-Soulier syndrome (defect in plt adhesion to vWF)
26
Pateint with ALL/CLL/AML/CML
ALL: Child CLL: Adult \>60 AML: Adult ~65 CML: Adult 30-60
28
CAH with hypotension
21-hydroxylase deficiency
29
Renal tumor
RCC: Associated with VHL and cigarettes Paraneoplastic syndromes (EPO, renin, PTH, ACTH)
30
Hereditary harmless jaundice
Gilbert syndrome (benign congenital unconjugated hyperbilirubinemia)
31
S3
Increased ventricular filling | (L-R shunt, MR, LV failure)
31
Stomach cancer
Adenocarcinoma
32
Osteomyelitis w/IVDU
Pseudomonas, S aureus
34
Arch of aorta aneurysm
Tertiary syphilis, vasa vasorum destruction
36
Cardiac tumor - adults
Mets, Primary myxoma (ball and valve, LA\>RA)
37
Rhabdomyoma
Tuberous sclerosis
38
HLA-DR3 or DR4
DM Type 1 RA SLE
39
Nosocomial pneumonia
Klebsiella, E coli, Pseudomonas
40
Mets to liver
Colon \>\> Stomach, pancreas
40
Site of diverticula
Sigmoid colon
41
Primary hyperparathyroidism
Adenomas, hyperplasia, carcinoma
42
S4
Stiff/hypertrophic ventricle (AS, Restrictive cardiomyopathy)
43
Testicular tumor
Seminoma (malignant, radiosensitive)
44
Esophageal cancer
SCC - worldwide Adeno - US
45
Mets to brain
Lung \> Breast \> GU \> Melanoma \> GI
46
Infection secondary to blood transfusion
Hepatitis C
48
Actinic keratosis
Precursor to SCC
49
t(14;18)
Follicular lymphoma (bcl-2 activation)
51
Myocarditis
Coxsackie B
52
t(9;22)
Philadelphia chromosome, CML
53
Heart valve in bacterial endocarditis
Mitral\> Aortic (rheumatic fever) Tricuspid (IV drug abuse)
54
Holosystolic murmur
VSD, TR, MR
55
Ejection click
Aortic/Pulmonic stenosis
57
Kidney stones
Calcium = radiopaque Struvite (ammonium) = radiopaque (formed by urease + organisms like proteus and staph) Uric acid = radiolucent
58
Death in CML
Blast crisis
60
Ovarian tumor (malignant)
Serous cystadenocarcinoma
62
Coronary artery involved in thrombosis
LAD\>RCA\>LCA
63
Neuron migration failure
Kallmann syndrome
64
Death in SLE
Lupus nephropathy
65
Type of Hodgkin
Nodular sclerosis (vs mixed cellularity, lymphocytic predominance, lymphocytic depletion)
66
Pituitary tumor
Prolactioma Somatotrophic acidophilic adenoma
67
Cerebellar tonsillar herniation
Chiari II malformation
69
Autoimmune chronic atrophic gastritis
Predisposition to gastric carcinoma (can also cause pernicious anemia)
70
Malignancy associated with noninfectious fever
Hodgkin lymphoma
72
RHF due to a pulmonary cause
Cor pulmonale
73
Primary bone tumor (adults)
Multiple myeloma
74
Helminth infection (US)
Enterobius vermicularis Ascaris lumbricoides
75
Secondary hyperparathyroidism
Hypocalcemia of chronic kidney disease
76
Constrictive pericarditis
TB (developing world) SLE (developed world)
77
Opening snap
Mitral stenosis
78
Ascending aorta aneurysm
Marfan (cystic medial degeneration)
79
Cardiac primary tumor in kids
Rhabdomyoma Often seen in tuberous sclerosis
80
Philadelphia chromosome
t(9;22) bcr-abl CML
81
Secondary hypertension
Renal disease
82
UTI
E Coli Staph saprophyticus
83
Mitral valve stenosis
Rheumatic heart disease
84
Mixed UMN and LMN motor neuron disease
ALS

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