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CARDIOLOGY > Key points > Flashcards

Key points Flashcards

1
Q

Aminosalicylates

A

Blood dyscrasias

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2
Q

Eluxolidine

A

Pancreatitis with/without Oddi spasm

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3
Q

Hyoscine butylbromide

A

Cardiac problems

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4
Q

PPI

A

Subacute cutaneous lupus erythematosus - rare

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5
Q

Loperamide

A

Risk of abuse/misuse, cardiac reaction
4-7 years - 3 days 1mg
8years - 5 days 2mg

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6
Q

Amiodarone

A

Photosensitivity, pulmonary toxicity, liver toxicity, thyroid disorder, corneal microdeposits, antivirals and bradycardia

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7
Q

Dronedarone

A

Hepatotoxicity, heart failure, pulmonary toxicity

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8
Q

Sotalol

A

QT interval prolongation

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9
Q

Tranexamic acid

A

Discontinue if visual disorders

Reduce dose - diarrhoea

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10
Q

Warfarin

A

Calciphylaxis

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11
Q

Beta blockers

A

Dry eye/rash - reversible on discontinuation, bradycardia

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12
Q

ACE inhibitor

A

Dry cough, angioedema, metallic, hepatotoxic

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13
Q

Statins

A

Interstitial lung disease, correct hypothyroidism before initiation, myopathy and myalgia

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14
Q

Thiazides

A

Gout, lupus, diabetes, eGFR under 30

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15
Q

Ivabradine

A

Do not initiate under 75bpm, stop below 50bpm

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16
Q

Nicorandil

A

Skin, mucosal and eye ulceration

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17
Q

Tiotropium

A

Capsule inhalation

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18
Q

OTC cough and cold

A

not under 6 and restricted 6 to 12 years

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19
Q

Desensitising vaccines

A

Anaphylaxis, specialist only

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20
Q

Hydroxyzine hydrochloride

A

QT interval prolongation and torsade de pointes

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21
Q

Leukotriene receptor antagonist

A

Churg strauss syndrome

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22
Q

Beclomethasone

A

Brand prescribing - vary in potency and particle size

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23
Q

Inhaled corticosteroid

A

Spacer, candidiasis, paradoxical bronchospasm, serous chorioretinopathy

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24
Q

LABA

A

Restricted prescribing

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25
Q

Opioids

A

Pinpoint pupils, naloxone, dependence

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26
Q

Metoclopramide

A

Dystonic reaction - 10mg TDS up to 5 days only

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27
Q

Domperidone

A

Cardiac reactions - 10mg TDS treatment only up to 7 days

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28
Q

Ergot derived dopamine agonist

A

Fibrotic reaction - ECG

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29
Q

Levodopa related

A

Impulse disorders

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30
Q

Lithium

A

Hypothyroidism, benign intracranial hypertension

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31
Q

Lisdexamfetamine

A

Cardiac function

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32
Q

Atomoxetine

A

Suicidal thoughts and growth

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33
Q

Dexamfetamine

A

Tics and tourettes - discontinue
Drug free period - growth catch up
Seizure - discontinue

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34
Q

Clozapine

A

Intestinal obstruction, agranulocytosis, cardiomyopathy, myositis, neutropenia

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35
Q

MAOI

A

Tyramine - discontinue frequent headaches and palpitations

36
Q

Methylphenidate

A

Psychiatric disorders

37
Q

Zonisamide

A

Fatal heat stroke

38
Q

Vigabatrin

A

Visual disorders, encephalopathic

39
Q

Phenytoin

A

blood and skin disorders, injectable error prone

40
Q

Gabapentin

A

Rosemont brand, risk of severe respiratory depression

41
Q

Lamotrigine

A

Skin reactions - SJS, TEN

42
Q

Fosphenytoin

A

Cardiac issues

43
Q

Carbamazepine

A

Blood dyscrasias, hepatic and skin disorders

44
Q

Antiepileptics

A

Depression

45
Q

Galantamine

A

Skin reactions

46
Q

Rivastigmine

A

Hydration - interrupt if dehydration

47
Q

Sodium valproate

A

Pancreatitis, liver toxicity

48
Q

Triptans

A

Sulfonamide hypersensitivity, discontinue in crushing pain in throat or chest

49
Q

Varenicline

A

Depression - discontinue

50
Q

Benzodiazepines

A

Paradoxical effects

51
Q

Antibiotic blood disorders

A

Linezolid, Trimethoprim, co-trimoxazole, gentamicin, vancomycin, sulfadiazine

52
Q

Flucloxacillin

A

Hepatitic disorder - 2 months

53
Q

Co-amoxiclav

A

Cholestatic jaundice - during or after treatment

54
Q

Tetracyclines

A

Benign intracranial hypertension

55
Q

Quinolones

A

Seizures, aortic dissection and aneurysm, tendon damage - 48 hours, restrictions

56
Q

Clindamycin

A

Diarrhoea - discontinue

57
Q

Linezolid

A

Blood dyscrasias, optic neuropathy, tyramine food

58
Q

Fusidic acid

A

Hepatotoxicity

59
Q

Co-trimoxazole

A

Restricted prescribing, blood dyscrasias

60
Q

Rifampin

A

Influenza - rifampicin syndrome

61
Q

Isoniazid

A

Peripheral neuropathy, hepatotoxic

62
Q

Ethambutol

A

Eye disorder

63
Q

Mefloquine

A

Depression

64
Q

Vancomycin

A

Discontinue if tinnitus

65
Q

Amphotericin

A

Brand = verify dose

66
Q

Gentamicin

A

Histamine related reactions

67
Q

Itraconazole

A

Heart failure

68
Q

Ketoconazole

A

Oral - MA retracted

Hepatotoxic

69
Q

Sucralfate

A

Bezoar formation

70
Q

Ibuprofen

A

Discontinue if rash occurs

71
Q

Tiaprofenic acid

A

Cystitis - discontinue

72
Q

Mefanamic acid

A

Diarrhoea and haemolytic anaemia - discontinue

73
Q

Piroxicam

A

Serious skin reaction

74
Q

IUD

A

Uterine perforation

75
Q

Oxytocin

A

Hyponatraemia

76
Q

Ulipristal acetate

A

Liver toxicity - uterine fibroids only

77
Q

Finasteride

A

Depression, breast cancer

78
Q

Tacrolimus

A

Macrolide hypersensitivity - contraindication
Hepatotoxic, neurotoxic, blood disorder, nephrotoxic, , eye disorder, skin disorder, hyperglycaemia, cardiovascular disorder

79
Q

Ciclosporin

A

Hepatotoxic, neurotoxic, nephrotoxic, blood disorders, benign intracranial hypertension

80
Q

Pioglitazone

A

Bladder cancer, cardiac issues, hepatotoxic

81
Q

DPP-4

A

pancreatitis

82
Q

SGLT2

A

Candida infection, lower limb amputation, ketoacidosis

83
Q

GLP-1

A

Pancreatitis

84
Q

Bisphosphonates

A

Osteonecrosis of the jaw, atypical femoral fractures, osteonecrosis of the auditory canal

85
Q

Carbimazole

A

Neutropenia, agranulocytosis, pancreatitis

86
Q

Propylthiouracil

A

Hepatotoxic

CARDIOLOGY (8 decks)

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