KIDNEY I

Question 1

PATHOLOGIC RESPONSES OF THE GLOMERULUS TO INJURY

Hypercellularity
The hypercellularity results from one or more of the following:
_________: Proliferation of mesangial or endothelial
_________, including neutrophils, monocytes and in some diseases, lymphocytes
__________

Answer 1

proliferation
infiltration of leukocytes
formation of crescents

Question 2

Glomerulonephritis resulting from deposition of circulating immune complexes

In this type of nephritis, _____________ is caused by the trapping of circulating antigen-antibody complexes within glomeruli

Answer 2

glomerular injury

Question 3

Mechanisms of Glomerular Injury following Immune Complex of Formation

Whatever the antigen may be, __________ formed or deposited in the glomeruli may elicit a local inflammatory reaction that produces

In summary, most cases of immune complex-mediated glomerulonephritis are a consequence of deposition of discrete immune complexes which give rise to granular immunofluorescence staining along the basement membranes or in the mesangium

Answer 3

antigen-antibody

Question 4

Nephritic syndrome
includes the ff:

HPAH

Answer 4

hematuria
proteinuria
azotemia
hypertension