kidneys Flashcards

(66 cards)

1
Q

how do plants take up nitrates and ammonium from the soil

A

facilitated diffusion and active transport

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2
Q

do plants excrete nitrogen-containing molecules?

A

no (only synthesise amino acids they need)

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3
Q

where are excess amino acids deaminated? what happens to the other molecules it is converted into?

A

the liver, they are excreted

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4
Q

do animals excrete nitrogen-containing molecules?

A

yes

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5
Q

what is deamination? and where does it take place?

A

removal of the amino group, which leaves NH3 and pyruvic acid, the liver

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6
Q

what happens to the ammonia in the liver

A

converted to urea

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7
Q

what can pyruvic acid be used for

A

for respiration as a source of energy or converted into fat and stored

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8
Q

draw an amino acid

A

H2 - N - CH(R) - C=O-OH

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9
Q

what type of animals excrete ammonia

A

aquatic animals

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10
Q

give 3 properties of ammonia molecules

A

small, very toxic, soluble

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11
Q

what occurs in soft-bodied invertebrates (to do with ammonia)

A

ammonia diffuses across the whole body surface into the surrounding water

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12
Q

what occurs in freshwater fish (to do with ammonia)

A

most of the ammonia is lost as ammonium ions across the epithelium of the gills

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13
Q

which animals excrete uric acid

A

snails, insects, birds and some reptiles

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14
Q

give 2 properties of uric acid

A

insoluble in water, non-toxic

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15
Q

how is urea excreted from the body

A

as urine

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16
Q

why can urea be transported in much higher concentrated form than ammonia

A

it is much less toxic (100,000x less)

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17
Q

what would the effect of not having urea breaking down ammonia

A

an animal would have to urinate in large amounts (ammonia is so toxic it can only be transported and excreted in a very dilute solution

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18
Q

what advantages does uric acid have over ammonia/urea

A

less toxic and reduces water loss (therefore need for water)

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19
Q

which macromolecules are broken down to produce nitrogen containing waste

A

proteins and nucleic acids

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20
Q

which artery/vein does each kidney receive blood from

A

renal artery

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21
Q

where does each kidney return blood to (via what)

A

to the vena cava via the renal vein

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22
Q

what does the renal cortex contain

A

bowman’s capsules / glomeruli (ultrafiltration)

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23
Q

what does the renal medulla contain

A

loops of Henle and collecting ducts

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24
Q

what does the renal pelvis do

A

empties urine into the ureter

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25
how does blood supply to the nephron begin
afferent arteriole to the glomerulus
26
how many nephrons are there in each kidney
1 million
27
what is a nephron
individual blood-filtering unit
28
what does PCT and DCT stand for
PCT= proximal convoluted tube DCT= distal convoluted tube
29
name the structures of the nephron (in order of blood flow)
renal (Bowman's) capsule, PCT, loop of Henle, DCT, collecting duct -- blood flowing through an afferent arteriole which has branched from the renal artery forms a capillary network - the glomerulus
30
give 2 functions of the kidneys
1. filter the blood to remove nitrogenous metabolic waste (urea and ammonium) to produce urine 2. osmoregulation (control of water and solute composition of body fluids)
31
what is excretion
removal of metabolic waste made by body (urine)
32
what is egestion
removal of undigested food (faeces)
33
what is secretion
release of useful substances
34
what's the difference between PCT and DCT and the collecting duct (structurally)
PCT has microvilli and DCT doesn't have microvilli and the collecting duct has individual cells showing easily
35
where does ultrafiltration take place
glomerulus (to Bowman's capsule)
36
definition of ultrafiltration
filtering of the blood into the nephron under high pressure
37
which arteriole has higher pressure and why (afferent/efferent)
efferent=higher pressure due to smaller lumen and blood has come from the left side of the heart
38
layers of ultrafiltration (glomerulus)
squamous endothelium, basement membrane (molecular sieve), podocytes (kidney cells)
39
why are the feet of the podocytes relevant
increase SA
40
where does selective reabsorption take place
PCT (proximal convoluted tubule)
41
name 6 adaptations of the PCT (proximal convoluted tubule)
- many mitochondria to produce ATP (for aerobic respiration) - microvilli to increase SA - capillaries nearby to reduce diffusion pathway - infolding of membrane on side next to capillaries to increase SA - many carrier and channel proteins - tight junctions between cells
42
describe the first step of selective reabsorption of glucose/amino acids
Na+ is actively transported out of the PCT cell and moves into the blood
43
(selective reabsorption) what's the result of Na+ being actively transported out of the PCT cell and into the blood
this decreases the concentration of Na+ in the PCT cell
44
(selective reabsorption) what happens after the Na+ concentration decreases in the PCT cell
Na+ moves into the cell from the filtrate down its concentration gradient -- through a co-transport protein (binded to glucose to move into the PCT cell)
45
(selective reabsorption) what happens after glucose/amino acids and Na+ ions move into the PCT cell
glucose leaves the PCT cells through a channel protein by facilitated diffusion
46
(selective reabsorption) how does the glucose/amino acids leave the PCT cell into the blood
facilitated diffusion down a concentration gradient into the blood
47
(selective reabsorption) how is the concentration gradient maintained as the glucose/amino acids leaves the PCT cell
the blood is always flowing
48
(selective reabsorption) what's another name for the reabsorption of glucose and ions
secondary active transport
49
(selective reabsorption) percentages for reabsorption of glucose, ions, amino acids, water, urea
glucose: 100% ions: 70% amino acid: 100% water: 90% urea: 50%
50
what's the main function of the loop of henle
actively transports ions out of the filtrate into the tissue fluid in the medulla
51
definition of negative feedback
if receptors detect a change away from a set point, corrective action takes place to return to that set point
52
definition of osmoregulation
control of water potential of the blood (solute concentration and water levels)
53
give 2 examples of positive feedback
labour (childbirth), blood clotting (platelets secrete signalling molecules which attract platelets)
54
what are target cells
they have receptors in membrane which are complementary to a specific hormone and only these cells will respond to that hormone
55
where is osmoregulation done
in the DCT (distal convoluted tubule) and collecting duct
56
(osmoregulation) whats the stimulus to produce more ADH (antidiuretic hormone)
lower water potential of blood in plasma
57
(osmoregulation) what are the receptors and where are they located
osmoreceptors in the hypothalamus
58
whats the coordinator in osmoregulation
posterior pituitary gland
59
does the pituitary gland produce more/less ADH for a low water potential
more
60
does the pituitary gland produce more/less ADH for a high water potential
less
61
(osmoregulation) what's the effector in low water potential
cells of the DCT (distal convoluted tubule) and collecting duct become more permeable to water
62
what's the response following the cells of DCT and collecting duct becoming more permeable
more water is reabsorbed into the blood from the filtrate
63
(osmoregulation) what's the result of more water being absorbed into the blood from the filtrate
smaller volume of blood but is more concentrated urine
64
(osmoregulation) what's the effector in high water potential
cells of the collecting duct and PCT become less permeable (due to aquaporins moving out of the membrane)
65
what's the response following the cells of DCT and collecting duct becoming less permeable
less water is reabsorbed from the collecting duct into the blood
66
(osmoregulation) what's the result of less water being absorbed into the blood from the filtrate
larger volume of more dilute urine produced