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Flashcards in Krafts - Study Questions Deck (19):
1

What tell you whether RBCs are normochromic or hypochromic?

Mean cell hemoglobin concentration (MCHC)

2

What tells you whether a patient's red cells are microcytic, normocytic or macrocytic?

Mean cell volume (MCV)

3

Anisocytosis refers to:

Variation in red cell size

4

-Massive blood loss, just occurred What is true of the sample of blood?

The hemoglobin will be normal.

5

Which type of anemia involves the attachment of IgG to red cells, which then get eaten up by macrophages in the spleen?

Warm autoimmune hemolytic anemia

6

What labs are consistent with a hemolytic process?

Increased bilirubin
Increased LDH
Decreased Haptoglobin
Increased Reticulocytes

7

What type of anemia involves the attachment of IgM and complement to red cells?

Cold autoimmune hemolytic anemia

8

The red cells in sickle cell disease are more susceptible to hemolysis because:

They possess an abnormal hemoglobin which polymerizes upon deoxygenation

9

28 yr old sister has low hemoglobin.
-Low RBC, Low MCV, High RCW
What is the most likely cause of her anemia?

Iron-deficiency anemia

10

Very poor, limited diet, developed numbness and weakness in extremities. Blood smear showed macrocytic anemia and hypersegmented neutrophils. Which of the following deficiencies is responsible for your grandfather's symptoms?

Vitamin B12

11

Very poor, limited diet, developed numbness and weakness in extremities. Blood smear showed macrocytic anemia and hyper-segmented neutrophils. Which of the following deficiencies is responsible for your grandfather's symptoms?

Vitamin B12

12

Worsening fatigue, shortness of breath, few episodes of pneumonia, diffuse petechiae scattered over arms and neck.
-Hgb low
-MCV normal
-RBC low
-WBC low
-Plt low
What is the most likely cause of anemia?

Aplastic anemia

13

What is a Heinz body?

"eaten out by macrophage bites"
-Denatured globin chains

14

Malignancy, obstetric complications, sepsis and trauma can all cause which of the following findings on blood smear?

Schistocytes (fragmented red cells)

15

Which of the following is true regarding the immunophenotype of normal peripheral blood?

Most lymphocytes are T cells

16

Which of the following blood findings is seen most commonly in infectious mononucleosis?

Reactive lymphocytosis

17

Your patient has elevated neutrophil count. The blood smear shows lots of unusual-looking neutrophils; some have abundant, dark-purple cytoplasmic granules, and other have lots of vacuoles in the cytoplasm. Which disorder is most likely to cause this finding?

E. coli - sepsis

18

-Elevated eosinophil count. Which disorder is the most likely cause?

Drug reaction

19

-Elevated basophil count. What should she be evaluated to see if she has:

Chronic myeloid leukemia