Micro-organisms - Skildum Flashcards
(26 cards)
What is the tropism for EBOV?
NK cells, Monocytes, Macrophages, Neutrophils
What is the tropism for HHV 6 & 7, HTLV 1 & 2, HIV 1 & 2?
T-lymphocytes
What is the tropism for EBV and HHV-8 (KSHV)?
B-lymphocytes
What is the tropism for CMV?
Monocytes & Macrophages
What is the tropism for Parvovirus B19?
BFU-E & CFU-E
What is the tropism for CTFV?
BFU-E, CFU-E, Red blood cells
Traits of EBOV?
(-)ssRNA virus
-Helical, Enveloped
Traits of CTFV?
dsRNA virus, segmented
-Icosahedral, Non-enveloped
Traits of HTLV-1 & 2, HIV 1 & 2?
Retroviruses
ssRNA, (+)
-Enveloped, Icosahedral
Traits of Parvovirus B19?
ssDNA, Non-enveloped, Icosahedral
Traits of EBV, CMV, HHV-6 & 7, KSHV?
Herpesviridae, dsDNA
-Enveloped, Icosahedral
What virus is non-icosahedral shaped? What is its shape?
Ebola virus (EBOV) Helical/Complex
What two viruses are non-enveloped?
CTFV, Parvovirus B19
What four viruses have a dsDNA genome?
Cytomegalovirus (CMV- HHV-5), HHV-6 & 7, EBV (HHV-4), Kaposi Sarcoma herpes virus (KSHV, HHV-8)
What four viruses have a dsDNA genome?
Herpes viruses!
Cytomegalovirus (CMV- HHV-5), HHV-6 & 7, EBV (HHV-4), Kaposi Sarcoma herpes virus (KSHV, HHV-8)
What is the CTFV genome?
dsRNA, segmented
What is the Parvovirus B19 genome?
ssDNA (pos. or neg.)
What is the HTLV-1, HTLV-2, HIV-1 and HIV-2 genome?
ssRNA, positive
What is the Ebola virus genome?
ssRNA negative
What virus do you use multiple anti-retrovirals to treat?
HIV-1 and HIV-2
What virus do you use chemotherapy and BMT to treat?
Human T lymphotrophic virus (HTLV-1, HTLV-2)
What virus do you use chemotherapy and BMT to treat?
Human T lymphotrophic virus (HTLV-1, HTLV-2)
What virus do you used Ganciclovir, Cidofir and foscarnet to treat?
Kaposi Sarcoma Herpes Virus (HHV-8)
What viruses do you just use supportive treatment for?
Ebola, Parvo B19, EBV, CTFV